Results 101 to 110 of about 665,812 (269)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Quantum State Designs with Clifford-Enhanced Matrix Product States

open access: yesPRX Quantum
Nonstabilizerness, or “magic,” is a critical quantum resource that, together with entanglement, characterizes the nonclassical complexity of quantum states.
Guglielmo Lami   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Site basis excitation Ansatz for matrix product states

open access: yesSciPost Physics Core
We introduce a simple and efficient variation of the tangent-space excitation Ansatz used to compute elementary excitation spectra of one-dimensional quantum lattice systems using matrix product states (MPS).
Steven R. White
doaj   +1 more source

Gaussian Matrix Product States

open access: yes, 2008
This work originally appeared as Sec. VII of quant-ph/0509166, and is published in the Proceedings on the conference on Quantum information and many body quantum systems, edited by M. Ericsson and S. Montangero, pg. 129 (Edizioni della Normale, Pisa, 2008)
Schuch, N., Cirac, J., Wolf, M.
openaire   +4 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A Method for Isomorphism Recognition of Kinematic Chain based on the Hamming Matrix and Connecting Rod Adjacency Matrix

open access: yesJixie chuandong, 2021
In the creative design of mechanical devices,the isomorphic kinematic chains should be eliminated to reduce the mechanism scheme for subsequent design and improve the design efficiency of mechanical device.
Changjun Wu   +4 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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