Results 101 to 110 of about 4,801,130 (303)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Language as a matrix product state

CoRR, 2017
We propose a statistical model for natural language that begins by considering language as a monoid, then representing it in complex matrices with a compatible translation invariant probability measure. We interpret the probability measure as arising via the Born rule from a translation invariant matrix product state.
Vasily Pestun, John Terilla, Yiannis Vlassopoulos   +2 more
openaire   +3 more sources

Product/Service Systems Experiences – an International Survey of Swedish, Japanese, Italian and German Manufacturing Companies [PDF]

, 2009
Organised by: Cranfield UniversityProduct/Service Systems have recently grown in manufacturers’ interest. This paper presents an international survey of manufacturers from Sweden, Japan, Italy and Germany.
Lindahl, Mattias, Shimomura, Y., Sakao, T., Sundin, Erik, Shimomura, Yoshiki, Lindahl, M., Sakao, Tomohiko, Sundin, E.   +7 more
core   +1 more source

Product-process interface for effective product design and manufacturing in a DFM approach [PDF]

, 2009
This research work is partly supported by SNECMA enterprise. It makes part of the MAIA 8 projectIn order to tackle a continuous improvement of virtual engineering, product modelling has to integrate always more knowledge that refer to every decision ...
El Gueder, Jawhar, ROUCOULES, Lionel, COCHENNEC, Florent, ROUHAUD, Emmanuelle, ELGUEDER, Jawhar   +4 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Efficiently Correcting Matrix Products [PDF]

, 2014
We study the problem of efficiently correcting an erroneous product of two \(n\times n\) matrices over a ring. We provide a randomized algorithm for correcting a matrix product with \(k\) erroneous entries running in \(\tilde{O}(\sqrt{k}n^2)\) time and a deterministic \(\tilde{O}(kn^2)\)-time algorithm for this problem (where the notation \(\tilde{O}\)
Leszek Gasieniec, Christos Levcopoulos, Andrzej Lingas   +2 more
openaire   +1 more source

Parent Lindbladians for matrix product density operators

Physical Review Research
Understanding quantum phases of matter is a fundamental goal in physics. For pure states, the representatives of phases are the ground states of locally interacting Hamiltonians, which are also renormalization fixed points (RFPs).
Yuhan Liu, Alberto Ruiz-de-Alarcón, Georgios Styliaris, Xiao-Qi Sun, David Pérez-García, J. Ignacio Cirac   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Products of commutators in matrix rings

Canadian Mathematical Bulletin
AbstractLet R be a ring and let $n\ge 2$ . We discuss the question of whether every element in the matrix ring $M_n(R)$ is a product of (additive) commutators $[x,y]=xy-yx$ , for $x,y\in M_n(R)$ . An example showing that this does not always hold, even when R is commutative, is provided.
Matej Brešar, Eusebio Gardella, Hannes Thiel   +2 more
openaire   +5 more sources