Results 81 to 90 of about 665,812 (269)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Transfer matrices and excitations with matrix product states

open access: yesNew Journal of Physics, 2015
We use the formalism of tensor network states to investigate the relation between static correlation functions in the ground state of local quantum many-body Hamiltonians and the dispersion relations of the corresponding low-energy excitations.
V Zauner   +8 more
doaj   +1 more source

Simplified State Interaction for Matrix Product State Wave Functions. [PDF]

open access: yesJ Chem Theory Comput, 2021
Freitag L   +3 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Multi-Modal Image Fusion Based on Matrix Product State of Tensor. [PDF]

open access: yesFront Neurorobot, 2021
Lu Y, Wang R, Gao Q, Sun D, Zhu.
europepmc   +1 more source

On Prime Matrix Product Factorizations

open access: yesCoRR
A graph $G$ factors into graphs $H$ and $K$ via a matrix product if $A = BC$, where $A$, $B$, and $C$ are the adjacency matrices of $G$, $H$, and $K$, respectively. The graph $G$ is prime if, in every such factorization, one of the factors is a perfect matching that is, it corresponds to a permutation matrix.
Saieed Akbari   +2 more
openaire   +2 more sources

Language as a matrix product state

open access: yesCoRR, 2017
We propose a statistical model for natural language that begins by considering language as a monoid, then representing it in complex matrices with a compatible translation invariant probability measure. We interpret the probability measure as arising via the Born rule from a translation invariant matrix product state.
Vasily Pestun   +2 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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