Results 61 to 70 of about 710,317 (313)

Improving product classification through product family segregation [PDF]

open access: yes, 2014
Information sources are invaluable when taking decisions in Product design especially at the front end of the design process. Product families if properly classified, the connectivity of product form and interaction of the features assist the designer in
Mohd. Ismail, Mohd. Shuisma   +2 more
core  

PRODUCT PORTFOLIO ANALYSIS - ARTHUR D. LITTLE MATRIX [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2011
In recent decades we have witnessed an unseen dynamism among companies, which is explained by their desire to engage in more activities that provide a high level of development and diversification. Thus, as companies are diversifying more and more, their
Curmei Catalin Valeriu   +1 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tensor product random matrix theory

open access: yesPhysical Review Research
The evolution of complex correlated quantum systems such as random circuit networks is governed by the dynamical buildup of both entanglement and entropy.
Alexander Altland   +2 more
doaj   +1 more source

Heat current in non-Markovian open systems

open access: yesNew Journal of Physics, 2023
We generalize time-evolving matrix product operators method to nonequilibrium quantum transport problems. The nonequilibrium current is obtained via numerical differentiation of the generating functional which is represented as a tensor network.
Ruofan Chen
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The Product Structure of Matrix Product States under Permutations

open access: yesPRX Quantum
Tensor network methods have proved to be highly effective in addressing a wide variety of physical scenarios, including those lacking an intrinsic one-dimensional geometry.
Marta Florido-Llinàs   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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