Results 71 to 80 of about 4,993,076 (256)

Dense QCD2 with matrix product states

open access: yesJournal of High Energy Physics
We study one-flavor SU(2) and SU(3) lattice QCD in (1 + 1) dimensions at zero temperature and finite density using matrix product states and the density matrix renormalization group.
Tomoya Hayata   +2 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Tensor quantum programming

open access: yesNew Journal of Physics
Running quantum algorithms often involves implementing complex quantum circuits with such a large number of multi-qubit gates that the challenge of tackling practical applications appears daunting.
A Termanova   +8 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Testing of a Structures Covariance Matrix for Three-Level Repeated Measures Data. [PDF]

open access: yes
This paper considers the problem of estimating, and testing for, a Kronecker product covariance structure of three-level (multiple time points (p), multiple sites (u), and multiple response variables (q)) multivariate data.
Ricardo Leiva, Anuradha Roy
core  

Higher structures in matrix product states [PDF]

open access: yes, 2023
For a parameterized family of invertible states (short-range-entangled states) in $(1+1)$ dimensions, we discuss a generalization of the Berry phase. Using translationally-invariant, infinite matrix product states (MPSs), we introduce a gerbe structure ...
Ryu, Shinsei, Ohyama, Shuhei
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On systolic arrays for complex matrix problems

open access: yes, 1989
We consider systolic arrays for matrix computations involving complex elements, and show that in certain circumstances the complex calculations can be decomposed into a number of real matrix sub-problems which can be used to good effect in reducing ...
Megson, G.M., Evans, D.J.
core   +1 more source

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