Results 221 to 230 of about 518,086 (284)

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Quantitative Elemental Oxides Analysis of Rock Cuttings Using Laser-Induced Breakdown Spectroscopy Coupled with Bayesian Optimization and Support Vector Machine. [PDF]

ACS Omega
Abu Alsaud S, Swanson A.
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

The Evaluation of Machine Learning Models Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae. [PDF]

Microbiologyopen
Fordham SME.
europepmc   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

Coal Air-Dry Basis Sulfur Content Detection Model Based on Hippopotamus Optimization Algorithm and Two Hidden Layer Extreme Learning Machine. [PDF]

ACS Omega
Liu D, Tian J, Zhu Z, Huang J, Xiao D.
europepmc   +1 more source

Link Prediction in Heterogeneous Information Networks: Improved Hypergraph Convolution with Adaptive Soft Voting. [PDF]

Entropy (Basel)
Zhang S, Huang Y, Luo Z, Zhou J, Wu B, Sun K, Mao H.   +6 more
europepmc   +1 more source

Maximum-entropy and subspace methods for high-resolution relaxation-diffusion distribution estimation. [PDF]

Imaging Neurosci (Camb)
Ning L.
europepmc   +1 more source

Phase Correction of MR Spectroscopic Imaging Data Using Model-Based Signal Estimation and Extrapolation. [PDF]

IEEE Trans Biomed Eng
Jin W, Guo R, Li Y, Zhao Y, Li X, Zhu XH, Chen W, Liang ZP.   +7 more
europepmc   +1 more source