Results 251 to 260 of about 156,207 (304)

Extracellular Matrix Stiffness Enhancement Promotes Docetaxel Resistance in Prostate Cancer via Inhibition of Apoptosis Mediated by Upregulation of PRRX1. [PDF]

Int J Med Sci
Chen J, Chen M, Xie Z, Shen L, Jiang J, Xia S.   +5 more
europepmc   +1 more source

Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction. [PDF]

Bone Res
Xu H, Wei K, Ni J, Deng X, Wang Y, Xiang T, Song F, Wang Q, Niu Y, Jiang F, Wang J, Sheng L, Dai J.   +12 more
europepmc   +1 more source

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness-Mediated Bimodal PD-L1/CXCL10 Regulation. [PDF]

Adv Sci (Weinh)
Zhang T, Li Y, Cheng B, Xu Z, Liu M, Feng J, Bai Y, Yu Y, Jiang P, Geng L, Xu F, Guo H.   +11 more
europepmc   +1 more source

Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming. [PDF]

Commun Biol
Zhao W, Yuan W, Dong T, Qi W, Feng Z, Li C, Sun Y.   +6 more
europepmc   +1 more source

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Locally assembled stiffness matrix: a novel method to obtain global stiffness matrix

Acta Mechanica, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xiao Han, Xingyue Sun, Xu Chen
openaire   +2 more sources

Impact of matrix stiffness on fibroblast function

Materials Science and Engineering: C, 2017
Chronic non-healing wounds, caused by impaired production of growth factors and reduced vascularization, represent a significant burden to patients, health care professionals, and health care system. While several wound dressing biomaterials have been developed, the impact of the mechanical properties of the dressings on the residing cells and ...
Hichem, El-Mohri, Yang, Wu, Swetaparna, Mohanty, Gargi, Ghosh   +3 more
openaire   +2 more sources

Matrix Stiffness: the Conductor of Organ Fibrosis

Current Rheumatology Reports, 2018
Organ fibrosis is a lethal component of scleroderma. The hallmark of scleroderma fibrosis is extensive extracellular matrix (ECM) deposition by activated myofibroblasts, specialized hyper-contractile cells that promote ECM remodeling and matrix stiffening.
Alba, Santos, David, Lagares
openaire   +2 more sources

Extracellular Matrix Stiffness in Lung Health and Disease

Comprehensive Physiology, 2022
Abstract The extracellular matrix (ECM) provides structural support and imparts a wide variety of environmental cues to cells. In the past decade, a growing body of work revealed that the mechanical properties of the ECM, commonly known as matrix stiffness, regulate the fundamental cellular processes of the lung ...
Ting, Guo, Chao, He, Aida, Venado, Yong, Zhou   +3 more
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Stiffness Matrix of Compliant Parallel Mehanisms

Volume 2: 32nd Mechanisms and Robotics Conference, Parts A and B, 2008
Starting from the definition of a stiffness matrix, the authors present the Cartesian stiffness matrix of parallel compliant mechanisms. The proposed formulation is more general than any other stiffness matrix found in the literature since it can take into account the stiffness of the passive joints and remains valid for large displacements.
C. Quennouelle, C. M. Gosselin
openaire   +1 more source

Affine connections for the Cartesian stiffness matrix

Proceedings of International Conference on Robotics and Automation, 2002
We study the 6/spl times/6 Cartesian stiffness matrix. We show that the stiffness of a rigid body subjected to conservative forces and moments is described by a (0,2) tensor which is the Hessian of the potential function. The key observation of the paper is that since the Hessian depends on the choice of an affine connection in the task space, so will ...
Milos Zefran, Vijay Kumar 0001
openaire   +1 more source