Results 71 to 80 of about 2,645,922 (287)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Matrix Theory, AdS/CFT, and Gauge/Gravity Correspondence

Advances in High Energy Physics, 2013
With N→∞  being fixed, R→∞, the free energy of the Matrix theory on a supergravity background F is a functional of F, W=W(R,F). We try to relate this functional with Seff(R,F), the effective action of F, where F is translation invariant along x-.
Shan Hu, Dimitri Nanopoulos
doaj   +1 more source

Emergent spacetime & quantum entanglement in matrix theory

Journal of High Energy Physics, 2017
In the context of the Bank-Fishler-Shenker-Susskind Matrix theory, we analyze a spherical membrane in light-cone M theory along with two asymptotically distant probes.
Vatche Sahakian, Yossathorn Tawabutr, Cynthia Yan   +2 more
doaj   +1 more source

Nonorthogonal density-matrix perturbation theory [PDF]

The Journal of Chemical Physics, 2005
Recursive density-matrix perturbation theory [A.M.N. Niklasson and M. Challacombe, Phys. Rev. Lett. 92, 193001 (2004)] provides an efficient framework for the linear scaling computation of materials response properties [V. Weber, A.M.N. Niklasson, and M. Challacombe, Phys. Rev. Lett. 92, 193002 (2004)]. In this article, we generalize the density-matrix
Niklasson, Anders M. N., Weber, Valery, Challacombe, Matt   +2 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A matrix model from string field theory

Frontiers in Physics, 2016
We demonstrate that a Hermitian matrix model can be derived from level truncated open string field theory with Chan-Paton factors. The Hermitian matrix is coupled with a scalar and U(N) vectors which are responsible for the D-brane at the tachyon vacuum.
Syoji Zeze
doaj   +1 more source

A Matrix Model Dual of Type 0B String Theory in Two Dimensions

, 2003
We propose that type 0B string theory in two dimensions admits a dual description in terms of a one dimensional bosonic matrix model of a hermitian matrix.
A. Dhar, A. Maloney, A. Sen, A. Sen, A. Sen, A. Strominger, A.A. Gerasimov, A.B. Zamolodchikov, A.M. Polyakov, A.M. Sengupta, B. Chen, C. Ahn, D. Gaiotto, D. Kutasov, D. Kutasov, D.J. Gross, E. Witten, E.J. Martinec, F. Larsen, G.W. Moore, G.W. Moore, I. Klebanov, I.R. Klebanov, I.R. Klebanov, I.R. Klebanov, J. Distler, J. McGreevy, J. McGreevy, J. Polchinski, J. Polchinski, J. Polchinski, J. Polchinski, J. Teschner, J.L. Karczmarek, J.M. Maldacena, K.-i. Aoki, M. Bianchi, M. Douglas, M. Gutperle, N. Lambert, N. Seiberg, Nicolaos Toumbas, O. Bergman, P. Di Francesco, P. Ginsparg, S.R. Das, S.Y. Alexandrov, T. Banks, T. Fukuda, T. Okuda, T. Takayanagi, Tadashi Takayanagi, V. Fateev   +52 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An Introduction to Wishart Matrix Moments

, 2018
These lecture notes provide a comprehensive, self-contained introduction to the analysis of Wishart matrix moments. This study may act as an introduction to some particular aspects of random matrix theory, or as a self-contained exposition of Wishart ...
Bishop, Adrian N., Del Moral, Pierre, Niclas, Angele   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source