Results 41 to 50 of about 3,705,438 (306)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Nonnegative Matrix Factorization with Transform Learning [PDF]
2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2018 Traditional NMF-based signal decomposition relies on the factorization of spectral data, which is typically computed by means of short-time frequency transform. In this paper we propose to relax the choice of a pre-fixed transform and learn a short-time orthogonal transform together with the factorization.
Dylan Fagot +2 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Matrix Transformations and Quasi-Newton Methods [PDF]
International Journal of Mathematics and Mathematical Sciences, 2007 We first recall some properties of infinite tridiagonal matrices considered as matrix transformations in sequence spaces of the formssξ,sξ∘,sξ(c), orlp(ξ). Then, we give some results on the finite section method for approximating a solution of an infinite linear system.
Boubakeur Benahmed +2 more
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Other title: Office of Children Services Transformation initial findings report
, 2020 "February 2020."; "Mike DeWine, Governor of Ohio; Jon Husted, Lt. Governor of Ohio."; "Ohio Governor's Children's Initiative, Children Services Transformation."; "Safe children. Stable homes.
Ohio. Children Services Transformation Advisory Council
core
Fibonacci difference sequence spaces for modulus functions
Le Matematiche, 2015 In the present paper we introduce Fibonacci difference sequence spaces l(F, Ƒ, p, u) and l_∞(F, Ƒ, p, u) by using a sequence of modulus functions and a new band matrix F.
Kuldip Raj, Suruchi Pandoh, Seema Jamwal
doaj
Convolution Calculation Optimization Method Based on Matrix Transformation [PDF]
Jisuanji gongcheng, 2019 An efficient convolution calculation optimization method MCFA based on matrix transformation is proposed.The input matrix is divided into blocks according to the width and the convolution core size of the output matrix.The input matrix sub-blocks and the
FANG Yuling, CHEN Qingkui
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source