Results 71 to 80 of about 434,628 (281)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Universal matrix transforms of holomorphic functions [PDF]
, 2006 The phenomenon of overconvergence is related with the convergence of subsequences of the sequence of partial sums of Taylor series at points outside their disk of convergence.
Bernal González, Luis +2 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Properties of Binomial Transforms for Modified (s,t)-Pell Matrix Sequence
Communications in Advanced Mathematical SciencesIn this study, we investigate a generalization of the modified Pell sequence, which is called $(s,t)$-modified Pell sequence. By considering this sequence, we define the matrix sequence whose elements are $(s,t)$-modified Pell numbers.
Ozan Haklıdır, Şükran Uygun
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Solving Fuzzy Volterra Integrodifferential Equations of Fractional Order by Bernoulli Wavelet Method
Advances in Fuzzy Systems, 2018 A matrix method called the Bernoulli wavelet method is presented for numerically solving the fuzzy fractional integrodifferential equations. Using the collocation points, this method transforms the fuzzy fractional integrodifferential equation to a ...
R. Mastani Shabestari +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A Note on the vec Operator Applied to Unbalanced Block-Structured Matrices
Journal of Applied Mathematics, 2016 The vec operator transforms a matrix to a column vector by stacking each column on top of the next. It is useful to write the vec of a block-structured matrix in terms of the vec operator applied to each of its component blocks.
Hal Caswell, Silke F. van Daalen
doaj +1 more source