Results 111 to 120 of about 607,422 (297)

ECONOMIC ANALYSIS OF THE POSSIBILITIES FOR BUSINESS PROCESSES IMPROVEMENT IN SERBIAN DAIRY INDUSTRY

open access: yesEkonomika Poljoprivrede (1979)
The objective of the research is to analyze the maturity model of business process management, evaluate the importance of the factors that form the basis of the model, as well as the mutual influence of certain factors on the level of maturity of ...
Milan Mihajlovic   +2 more
doaj   +1 more source

Life-history variation and age at maturity in Eurasian Perch (Perca fluviatilis L.) [PDF]

open access: yes, 2003
This thesis deals with life-history variation in perch, with special focus on age at maturity. We conducted field studies to uncover the variation within short geographic distances and a literature review to study variation on a large geographic scale in
Heibo, Erik
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Modelos de madurez y su idoneidad para aplicar en pequeñas y medianas empresas / Maturity models and the suitability of its application in small and medium enterprises

open access: yesRevista Científica de Ingeniería Industrial, 2014
Actualmente, existen metodologías, estándares, modelos de madurez y guías que pueden ayudar a una organización a mejorar su modo de operar. Los modelos de madurez constituyen una evolución de las metodologías para gestionar la calidad de la ...
Elizabeth Pérez-Mergarejo   +2 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Maturity assessment and maturity models in health care: A multivocal literature review. [PDF]

open access: yesDigit Health, 2020
Kolukısa Tarhan A   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Determinants of euro term structure of credit spreads [PDF]

open access: yes
In this paper, we investigate the determinants of the Euro term structure of credit spreads. More specifically, we analyze whether the sensitivity of credit spread changes to financial and macroeconomic variables depends on bond characteristics such as ...
Van Landschoot, Astrid
core  

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