Results 61 to 70 of about 100,072 (310)
Digital Transformation Journey Guidance: A Holistic Digital Maturity Model Based on a Systematic Literature Review [PDF]
, 2023 Arzu Aras, Gülçin Büyüközkan
openalex +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A maturity model for Clinical Trials Management Ecosystem
Journal of Clinical and Translational ScienceIntroduction: Managing clinical trials is a complex process requiring careful integration of human, technology, compliance, and operations for success.
Shruti Sehgal +9 more
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Maturity Models for Systems Thinking
Systems, 2018 Recent decades have seen a rapid increase in the complexity of goods, products, and services that society has come to demand. This has necessitated a corresponding growth in the requirements demanded of organizational systems and the people who work in ...
Pamela Buckle
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A systematic literature review on quality maturity models [PDF]
TehnikaThis paper systematises the most commonly used maturity models of quality management systems in organisational systems. It is well known that the application of maturity models for quality management systems facilitates the improvement of organisational ...
Živković Nedeljka N. +2 more
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Digital health and capability maturity models-a critical thematic review and conceptual synthesis of the literature. [PDF]
J Am Med Inform Assoc, 2023 Liaw ST, Godinho MA.
europepmc +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source