Results 71 to 80 of about 100,072 (310)

TINGKAT KEMATANGAN MANAJEMEN PROYEK: SURVEI DI BEBERAPA TEMPAT DI INDONESIA

open access: yesCivil Engineering Dimension, 2005
This paper presents the results of a pilot survey aimed at ascertaining the level of project management maturity in Indonesian companies. Kerzner’s Level 2 assessment tool was used, which basically assesses maturity levels throughout the various phases
Achmad Fuad Bay   +2 more
doaj  

Which one? A suggested approach for evaluating digital health maturity models. [PDF]

open access: yesFront Digit Health, 2022
Woods L   +5 more
europepmc   +1 more source

Maturity Models

open access: yes, 2016
Recent advancements in set theory and readily available software have enabled social science researchers to bridge the variable-centered quantitative and case-based qualitative methodological paradigms in order to analyze multi-dimensional associations beyond the linearity assumptions, aggregate effects, unicausal reduction, and case specificity. Based
Lasrado, Lester Allan, Vatrapu, Ravi
openaire   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Advancing maturity modeling for precision oncology

open access: yesJournal of Clinical and Translational Science
Introduction: This study aimed to map the maturity of precision oncology as an example of a Learning Health System by understanding the current state of practice, tools and informatics, and barriers and facilitators of maturity.
Ariella Hoffman-Peterson   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Artificial Intelligence and Machine Learning for Maturity Evaluation and Model Validation [PDF]

open access: gold, 2022
Thomas Hanne   +4 more
openalex   +1 more source

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