Results 61 to 70 of about 8,466 (229)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Inertias of block band matrix completions
, 2015 The full set of completion inertias is described in terms of seven linear inequalities involving inertias and ranks of specified submatrices. The minimal completion rank for P is computed. We study the completion inertias of partially specified hermitian
Dancis, J, Cohen, N
core +1 more source
Representation Dimensions of Algebraic Tori and Symmetric Ranks of G-Lattices [PDF]
Algebraic tori over a field k are special examples of affine group schemes over k, such as the multiplicative group of the field or the unit circle. Any algebraic torus can be embedded into the group of invertible n x n matrices with entries in k for ...
Heath, Jason Bailey
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On minimal solutions of the matrix equation AX−YB=0
, 2001 In the case when one of the ranks of matrices A or B is full, all self-adjoint pairs of solutions of the equation AX−YB=0 are given. Necessary and sufficient conditions for the existence of nonnegative and positive definite solutions are proved.
Mirko Dobovišek
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
RANKS OF THE COMMON SOLUTION TO SOME QUATERNION MATRIX EQUATIONS WITH APPLICATIONS
, 2012 . We derive the formulas of the maximal and minimal ranks of four real matrices X1, X2, X3 and X4 in common solution X = X1 + X2i + X3j + X4k to quaternion matrix equations A1X = C1, XB2 = C2, A3XB3 = C3.
Q W Wang, S W Yu
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Lattice-Ordered Algebras That are Subdirect Products of Valuation Domains [PDF]
, 1994 An f-ring (i.e., a lattice-ordered ring that is a subdirect product of totally ordered rings) A is called an SV-ring if A/P is a valuation domain for every prime ideal P of A.
Jorge Martinez +7 more
core +1 more source