Results 71 to 80 of about 2,189,668 (351)

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1075-1085, April 2025.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Variation Inequalities for the Hardy-Littlewood Maximal Function on Finite Directed Graphs

open access: yesMathematics, 2022
In this paper, the authors establish the bounds for the Hardy-Littlewood maximal operator defined on a finite directed graph G→ in the space BVp(G→) of bounded p-variation functions.
Feng Liu, Xiao Zhang
doaj   +1 more source

Poincaré inequalities for the maximal function [PDF]

open access: yesANNALI SCUOLA NORMALE SUPERIORE - CLASSE DI SCIENZE, 2019
19 pages, 1 figure, a change in the abstract and a mistake removed. The application to $W^{1,1}$ reproduces the known results but does not improve them.
openaire   +5 more sources

The Hilbert Function of a Maximal Cohen-Macaulay Module

open access: yes, 2004
We study Hilbert functions of maximal Cohen-Macaulay(=CM) modules over CM local rings. We show that if $A$ is a hypersurface ring with dimension $d > 0$ then the Hilbert function of $M$ \wrt $\m$ is non-decreasing.
Puthenpurakal, Tony J.
core   +4 more sources

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, Volume 599, Issue 7, Page 952-970, April 2025.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Maximal and minimal iterative positive solutions for p-Laplacian Hadamard fractional differential equations with the derivative term contained in the nonlinear term

open access: yesAIMS Mathematics, 2021
In this paper, the maximal and minimal iterative positive solutions are investigated for a singular Hadamard fractional differential equation boundary value problem with a boundary condition involving values at infinite number of points. Green's function
Limin Guo, Lishan Liu, Ying Wang
doaj   +1 more source

Two-weight inequalities for multilinear maximal functions in Orlicz spaces [PDF]

open access: yesarXiv, 2022
In this note, we provide various two-weight norm estimates of the multi-linear fractional maximal function and weighted maximal function between different Orlicz spaces. More precisely, we obtain Sawyer-type characterizations and norm estimates for these operators.
arxiv  

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1113-1121, April 2025.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Maximal subextension and stability on $m$-capacity of maximal subextension of $m$-subharmonic functions with given boundary values [PDF]

open access: yesarXiv, 2023
In this paper, we study maximal subextension of $m$-subharmonic functions with given boundary values. We also prove stability on $m$-capacity of maximal subextension of $m$-subharmonic functions with given boundary values.
arxiv  

Variation of the Dyadic Maximal Function

open access: yesInternational Mathematics Research Notices, 2022
AbstractWe prove that for the dyadic maximal operator $\textrm {M}$ and every locally integrable function $f\in L^1_{{\textrm {loc}}}(\mathbb R^d)$ with bounded variation, also $\textrm {M} f$ is locally integrable and $\mathop {\textrm {var}}\textrm {M} f\leq C_d\mathop {\textrm {var}} f$ for any dimension $d\geq 1$.
openaire   +2 more sources

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