Results 91 to 100 of about 988,365 (280)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Fusion systems on maximal class 3-groups of rank two revisited [PDF]
We complete the determination of saturated fusion systems on maximal class 3-groups of rank ...
Chris Parker (190905) +3 more
core +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Classification and Types of Bases of All Ultrafunctions on Two-Element Set
This paper studies properties of ultrafunctions with respect of their inclusion in maximal clones. The number of maximal clones for all ultrafunctions of rank 2 is equal to 11 [V. Panteleev, 2009].
S. Zamaratskaya, V. Panteleev
doaj
Classical weight-four L-value ratios as sums of Calabi-Yau invariants
We revisit the series solutions of the attractor equations of 4d $\mathcal{N}=2$ supergravities obtained by Calabi–Yau compactifications previously studied in [P. Candelas et al., J. High Energy Phys. 11, 032 (2021)].
Philip Candelas, Xenia de la Ossa, Joseph McGovern
doaj +1 more source
The generic structure and some peculiarities of real rank one solvable Lie algebras possessing a maximal torus of derivations with the eigenvalue spectrum spec ( t ) = 1 , k , k + 1 , ⋯ , n + k − 3 , n + 2 k − 3 for k ≥ 2
Rutwig Campoamor-Stursberg +1 more
doaj +1 more source
Let C be a general curve of genus g, embedded in P^r via a general linear series of degree d. In this paper, we prove the Maximal Rank Conjecture, which determines the Hilbert function of C.
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Optical communications through highly scattering channels using the coherence-rank
In optical communications, logical bits are encoded in physical degrees-of-freedom (DoFs) of the electromagnetic field. Consequently, optical scattering in a communications channel compromises the information transfer.
Mitchell Harling +3 more
doaj +1 more source

