Results 101 to 110 of about 6,663,186 (371)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Enhanced Instability of de Sitter Space in Einstein-Gauss-Bonnet Gravity
, 2009 We show that the addition of a topological Gauss-Bonnet term to the gravitational action can greatly increase the instability of four-dimensional de Sitter space, by favoring the nucleation of black holes.
Maulik Parikh, S. W. Hawking
core +1 more source
Asian Journal of Sports Medicine, 2012 Purpose Prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. This study examined the effect of short-term maximal exercise on these markers, homocysteine levels (Hcy), and total antioxidant status (TAS ...
Omar Hammouda +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Long-term fluctuations of snow cover thickness and maximum snow storage in Gis-Baikal area
Лëд и снег, 2015 The paper describes the variability of snow depth and maximal snow storage at level of biogeographical areas and provinces for the long-term period of 1961–2010.
E. V. Maksyutova
doaj +1 more source
A Characterization of Vitali Conditions in Terms of Maximal Inequalities
The Annals of Probability, 1980 Vitali conditions $V, V', V_p, 1 \leqslant p < \infty$, on $\sigma$-algebras indexed by a directed set, are shown to hold if and only if the maximal inequality \begin{equation*}\tag{1} P(\text{essential} \lim \sup X_t \geqslant \alpha) \leqslant K \lim \sup_{T^\ast}E(X_\tau)/\alpha\end{equation*} holds for all adapted positive processes $(X_t)$, and ...
Millet, Annie, Sucheston, Louis
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Nonlinear parabolic problems in Musielak--Orlicz spaces [PDF]
, 2013 Our studies are directed to the existence of weak solutions to a parabolic problem containing a multi-valued term. The problem is formulated in the language of maximal monotone graphs.
Świerczewska-Gwiazda, Agnieszka
core
On the Maximal Quantity of Processed Information in the Physical Eschatological Context
, 2001 An estimate of the maximal informational content available to advanced extraterrestrial or future (post)human civilizations is presented. It is shown that the fundamental thermodynamical considerations may lead to a quantitative estimate of the largest ...
Cirkovic, Milan M., Radujkov, Marina
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source