Results 91 to 100 of about 385,717 (303)

Respostas neuromusculares e fisiológicas entre protocolo intermitente e contínuo de fadiga no ciclismo [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2015.O objetivo do presente estudo foi investigar e comparar o processo de fadiga em ciclistas e triatletas
Berneira, Joscelito de Oliveira
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Respiratory system responses to a maximal apnoea

A maximal apnoea provides significant challenges to one's physiological systems, including significantly altered arterial blood gases, and requires a highly integrative response from multiple systems, that is, changes in blood pressure, maintenance of ...
Troy J. Cross, Cross, TJ, Dario Vrdoljak, Foretic, N, Joseph W. Duke, Garrett Z. Merdich, Duke, JW, Vrdoljak, D, Željko Dujić, Colin D. Hubbard, Merdich, GZ, Hubbard, CD, Dujić, Ž, Nikola Foretic   +13 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Short term effects of vibration training on maximal shoulder push up

Physical Treatments, 2012
Objective: Recently, whole body vibration exercise has been developed as a new modality in the field of physiotherapy. It has been suggested that this exercise increases muscle power and strength and improves muscular performance.
Afsun Nodehi Moghadami, Roshanak keshavarz, Ebrahem Ali koozahei, Hooman Minoonejad, Mojtaba Ebrahimi werkiani   +4 more
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Efeito de quatro semanas de treinamento sobre os índices de aptidão aeróbia e força muscular: influência da intensidade e da oclusão de fluxo sanguíneo [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2014.O objetivo deste estudo foi analisar e comparar os efeitos de quatro diferentes tipos de treinamento aeróbio
Oliveira, Mariana Fernandes Mendes de
core  

Maximal dissipativity of Kolmogorov operators with Cahn–Hilliard type drift term

, 2009
We prove the existence of invariant measures μ for Kolmogorov operators LF associated with semilinear stochastic partial differential equations with Cahn–Hilliard type drift term. Based on gradient estimates on the pseudo-resolvent associated with LF and
Es-Sarhir, Abdelhadi, Stannat, Wilhelm
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Variable Versus Constant Resistance Squat Training for Lower-Limb Strength and Power: A Systematic Review and Meta-Analysis

Applied Sciences
The superiority of Variable Resistance Training (VRT) over traditional Constant Resistance Training (CRT) for enhancing lower-limb performance is debated, with previous meta-analyses limited by aggregating disparate exercises.
Zhijie Yan, Juncheng Wu, Shengfa Lin, Qi Li, Ruidong Liu   +4 more
doaj   +1 more source