Results 101 to 110 of about 1,172,217 (295)

Periodic optimal control for biomass productivity maximization in a photobioreactor using natural light [PDF]

open access: yes, 2012
We address the question of optimization of the microalgal biomass long term productivity in the framework of production in photobioreactors under the influence of day/night cycles.
Akhmetzhanov, Andrei R.   +2 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Global existence for a singular phase field system related to a sliding mode control problem

open access: yes, 2017
In the present contribution we consider a singular phase field system located in a smooth and bounded three-dimensional domain. The entropy balance equation is perturbed by a logarithmic nonlinearity and by the presence of an additional term involving a ...
Colli, Pierluigi, Colturato, Michele
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Variable Versus Constant Resistance Squat Training for Lower-Limb Strength and Power: A Systematic Review and Meta-Analysis

open access: yesApplied Sciences
The superiority of Variable Resistance Training (VRT) over traditional Constant Resistance Training (CRT) for enhancing lower-limb performance is debated, with previous meta-analyses limited by aggregating disparate exercises.
Zhijie Yan   +4 more
doaj   +1 more source

Three-term exponential asymptotic for the maximal term of an entire Dirichlet series (in Ukrainian)

open access: yesMatematychni Studii, 2011
Conditions on the coefficients and the exponents of an entireDirichlet series, under which for its maximal term the asymptoticequality$lnmu(sigma)=T_1e^{varrho_1sigma}+T_2e^{varrho_2sigma}+(au+o(1))e^{varrhosigma}$ $(sigmao +infty)$ is valid, where ...
М. М. Hrytsiv, М. М. Sheremeta
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Influence of the Enzyme Membrane Thickness on the Response of Amperometric Biosensors

open access: yesSensors, 2003
A mathematical model of amperometric biosensors has been developed. The model is based on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetics of the enzymatic reaction.
Juozas Kulys   +2 more
doaj   +1 more source

Groups whose locally maximal product-free sets are complete [PDF]

open access: yes, 2018
Let G be a finite group and S a subset of G. Then S is product-free if S ∩ SS = ∅, and complete if G∗ ⊆ S ∪ SS. A product-free set is locally maximal if it is not contained in a strictly larger product-free set.
Anabanti, Chimere S.   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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