Results 71 to 80 of about 4,739,268 (353)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Vibration response analysis of footbridge based on pedestrian perception

open access: yesAdvances in Bridge Engineering, 2023
This article aims to study the influence of random crowd loading on the perceived vibration response of pedestrians. Firstly, a vertical vibration response analysis method considering pedestrian perception was established based on the random crowd ...
Yuhao Feng   +4 more
doaj   +1 more source

Influence of gas compression on flame acceleration in the early stage of burning in tubes

open access: yes, 2012
The mechanism of finger flame acceleration at the early stage of burning in tubes was studied experimentally by Clanet and Searby [Combust. Flame 105: 225 (1996)] for slow propane-air flames, and elucidated analytically and computationally by Bychkov et ...
Akkerman, V'yacheslav   +5 more
core   +1 more source

GPU Accelerated Maximum Cardinality Matching Algorithms for Bipartite Graphs [PDF]

open access: yes, 2013
14 pages, 5 ...
Deveci, Mehmet   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Seismic Hazard Assessment and Determination of Maximum Design Base Acceleration of Yazd [PDF]

open access: yesJournal of Rehabilitation in Civil Engineering, 2014
According to Iranian code of practice for seismic resistant design of buildings standard No. 2800, Yazd is located in the place with the medium earthquake hazard [1].
Azita Asadi   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Optimal earthquake intensity measures for probabilistic seismic demand models of ARP1400 reactor containment building

open access: yesNuclear Engineering and Technology, 2021
This study identifies efficient earthquake intensity measures (IMs) for seismic performances and fragility evaluations of the reactor containment building (RCB) in the advanced power reactor 1400 (APR1400) nuclear power plant (NPP).
Duy-Duan Nguyen   +4 more
doaj   +1 more source

Kinetic approaches to particle acceleration at cosmic ray modified shocks

open access: yes, 2008
Kinetic approaches provide an effective description of the process of particle acceleration at shock fronts and allow to take into account the dynamical reaction of the accelerated particles as well as the amplification of the turbulent magnetic field as
Amato E.   +15 more
core   +1 more source

Non-thermal particle acceleration from maximum entropy in collisionless plasmas

open access: yesJournal of Plasma Physics, 2022
Dissipative processes cause collisionless plasmas in many systems to develop non-thermal particle distributions with broad power-law tails. The prevalence of power-law energy distributions in space/astrophysical observations and kinetic simulations of systems with a variety of acceleration and trapping (or escape) mechanisms poses a deep mystery.
openaire   +2 more sources

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