Results 61 to 70 of about 1,156,434 (264)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Laplacian Integral Graphs with Maximum Degree $3$ [PDF]
The Electronic Journal of Combinatorics, 2008 A graph is said to be Laplacian integral if the spectrum of its Laplacian matrix consists entirely of integers. Using combinatorial and matrix-theoretic techniques, we identify, up to isomorphism, the $21$ connected Laplacian integral graphs of maximum degree $3$ on at least $6$ vertices.
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
, 2016 A graph H is a square root of a graph G if G can be obtained from H by adding an edge between any two vertices in H that are of distance 2. The Square Root problem is that of deciding whether a given graph admits a square root. This problem is only known to be NP-complete for chordal graphs and polynomial-time solvable for non-trivial minor-closed ...
Cochefert, Manfred +5 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
On chromatic vertex stability of 3-chromatic graphs with maximum degree 4 [PDF]
Discrete Mathematics Letters, 2022 Martin Knor +2 more
doaj +1 more source
Waiter-Client Maximum Degree Game
, 2018 For integers $n, D, q$ we define a two player perfect information game with no chance moves called the Waiter-Client Maximum Degree game. In this game, two players (Waiter and Client) play on the edges of $K_n$ as follows: in each round, Waiter offers $q+1$ edges which have not been previously offered.
Krivelevich, Michael, Trumer, Nadav
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Total vertex irregularity strength of trees with maximum degree five
Electronic Journal of Graph Theory and Applications, 2018 In 2010, Nurdin, Baskoro, Salman and Gaos conjectured that the total vertex irregularity strength of any tree T is determined only by the number of vertices of degrees 1, 2 and 3 in T. This paper will confirm this conjecture by considering all trees with
S. Susilawati +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source