Results 51 to 60 of about 32,653 (280)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Some Notes on Maximum Entropy Utility

open access: yesEntropy, 2019
The maximum entropy principle is effective in solving decision problems, especially when it is not possible to obtain sufficient information to induce a decision.
Eun Young Kim, Byeong Seok Ahn
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Entropy production and lost work for irreversible processes [PDF]

open access: yes, 2006
In this paper we analyse in depth the Lost Work in an irreversible process (i.e. IRREV REV Lost ) W =W -W . This quantity is also called ‘degraded energy’ or ‘Energy unavailable to do work’. Usually in textbooks one can find the relation Lost U W o TDS .
Di Liberto, Francesco
core   +1 more source

Maximum Entropy Theory of Ecology: A Reply to Harte

open access: yesEntropy, 2018
In a paper published in this journal, I addressed the following problem: under which conditions will two scientists, observing the same system and sharing the same initial information, reach the same probabilistic description upon the application of the ...
Marco Favretti
doaj   +1 more source

Statistics and quantum maximum entropy principle

open access: yesIl Nuovo Cimento C, 2010
By using the reduced Wigner formalism we consider a kinetic theory for a quantum gas. We introduce a set of generalized kinetic fields and obtain a hierarchy of Quantum Hydrodynamic (QHD) equations for the corresponding macroscopic variables. To close the QHD system a maximum entropy principle is asserted, and to explicitly incorporate particles ...
TROVATO, Massimo, REGGIANI L.
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Atomic Structure Modeling of Multi-Principal-Element Alloys by the Principle of Maximum Entropy

open access: yesEntropy, 2013
Atomic structure models of multi-principal-element alloys (or high-entropy alloys) composed of four to eight componential elements in both BCC and FCC lattice structures are built according to the principle of maximum entropy.
Shaoqing Wang
doaj   +1 more source

(Generalized) Maximum Cumulative Direct, Residual, and Paired Φ Entropy Approach

open access: yesEntropy, 2020
A distribution that maximizes an entropy can be found by applying two different principles. On the one hand, Jaynes (1957a,b) formulated the maximum entropy principle (MaxEnt) as the search for a distribution maximizing a given entropy under some given ...
Ingo Klein, Monika Doll
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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