Results 41 to 50 of about 32,653 (280)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Проблеми трибології, 2022 The article gives a thermodynamic substantiation of the direction of nonequilibrium processes in tribocouples of machine parts, in tribosystems, based on the principles of maximum and minimum entropy.
V.V. Aulin +3 more
doaj +1 more source
The maximum entropy principle and the nature of fractals [PDF]
Physica A: Statistical Mechanics and its Applications, 1998 7 pages, RevTex, includes 2 PS ...
Pastor Satorras, Romualdo +1 more
openaire +4 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Entropy production in an energy balance Daisyworld model [PDF]
, 2008 Daisyworld is a simple mathematical model of a planetary system that exhibits self-regulation due to the nature of feedback between life and its environment.
Dyke, J. G.
core
Maximum Entropy Production Principle and Morphological Selection in Hydrodynamic Systems
Proceedings, 2017 In recent decades an idea has emerged that the maximum entropy production principle can be used to select from the different regimes of development of nonequilibrium systems. According to this principle the process with maximum entropy production is most
Anna Birzina, Leonid Martyushev
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Self-organized complexity and Coherent Infomax from the viewpoint of Jaynes’s probability theory [PDF]
, 2012 This paper discusses concepts of self-organized complexity and the theory of Coherent Infomax in the light of Jaynes’s probability theory. Coherent Infomax, shows, in principle, how adaptively self-organized complexity can be preserved and improved by ...
Phillips, William A. +2 more
core +1 more source
Training Concept, Evolution Time, and the Maximum Entropy Production Principle
Entropy, 2016 The maximum entropy production principle (MEPP) is a type of entropy optimization which demands that complex non-equilibrium systems should organize such that the rate of the entropy production is maximized. Our take on this principle is that to prove or
Alexey Bezryadin, Erik Kountz
doaj +1 more source
Entropy-Based Temporal Downscaling of Precipitation as Tool for Sediment Delivery Ratio Assessment
Entropy, 2021 Many regions around the globe are subjected to precipitation-data scarcity that often hinders the capacity of hydrological modeling. The entropy theory and the principle of maximum entropy can help hydrologists to extract useful information from the ...
Pedro Henrique Lima Alencar +2 more
doaj +1 more source