Results 41 to 50 of about 3,290,751 (273)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Pricing Interval European Option with the Principle of Maximum Entropy
Entropy, 2019 This paper develops the interval maximum entropy model for the interval European option valuation by estimating an underlying asset distribution. The refined solution for the model is obtained by the Lagrange multiplier.
Xiao Liu +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The maximum entropy principle and the nature of fractals [PDF]
Physica A: Statistical Mechanics and its Applications, 1998 7 pages, RevTex, includes 2 PS ...
Pastor Satorras, Romualdo +1 more
openaire +4 more sources
Проблеми трибології, 2022 The article gives a thermodynamic substantiation of the direction of nonequilibrium processes in tribocouples of machine parts, in tribosystems, based on the principles of maximum and minimum entropy.
V.V. Aulin +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Maximum Entropy Production Principle and Morphological Selection in Hydrodynamic Systems
Proceedings, 2017 In recent decades an idea has emerged that the maximum entropy production principle can be used to select from the different regimes of development of nonequilibrium systems. According to this principle the process with maximum entropy production is most
Anna Birzina, Leonid Martyushev
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Statistics and quantum maximum entropy principle
Il Nuovo Cimento C, 2010 By using the reduced Wigner formalism we consider a kinetic theory for a quantum gas. We introduce a set of generalized kinetic fields and obtain a hierarchy of Quantum Hydrodynamic (QHD) equations for the corresponding macroscopic variables. To close the QHD system a maximum entropy principle is asserted, and to explicitly incorporate particles ...
TROVATO, Massimo, REGGIANI L.
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Training Concept, Evolution Time, and the Maximum Entropy Production Principle
Entropy, 2016 The maximum entropy production principle (MEPP) is a type of entropy optimization which demands that complex non-equilibrium systems should organize such that the rate of the entropy production is maximized. Our take on this principle is that to prove or
Alexey Bezryadin, Erik Kountz
doaj +1 more source