Results 61 to 70 of about 8,987,758 (280)

A Statistical Inference of the Principle of Maximum Entropy Production

open access: yes, 2021
The maximization of entropy S within a closed system is accepted as an inevitability (as the second law of thermodynamics) by statistical inference alone. The Maximum Entropy Production Principle (MEPP) states that not only S maximizes, but $\dot{S}$ as well: a system will dissipate as fast as possible.
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Entropy production in an energy balance Daisyworld model

open access: yes, 2008
Daisyworld is a simple mathematical model of a planetary system that exhibits self-regulation due to the nature of feedback between life and its environment.
Dyke, J. G.
core   +1 more source

Using Maximum Entropy Production to Describe Microbial Biogeochemistry Over Time and Space in a Meromictic Pond

open access: yesFrontiers in Environmental Science, 2018
Determining how microbial communities organize and function at the ecosystem level is essential to understanding and predicting how they will respond to environmental change.
Joseph J. Vallino, Julie A. Huber
doaj   +1 more source

Maximum Entropy Production and Maximum Shannon Entropy as Germane Principles for the Evolution of Enzyme Kinetics

open access: yes, 2013
There have been many attempts to use optimization approaches to study the biological evolution of enzyme kinetics. Our basic assumption here is that the biological evolution of catalytic cycle fluxes between enzyme internal functional states is accompanied by increased entropy production of the fluxes and increased Shannon information entropy of the ...
Juretić, Davor   +3 more
openaire   +1 more source

Mammographic image restoration using maximum entropy deconvolution [PDF]

open access: yes, 2004
Bayesian maximum entropy method (MEM) has been applied to a radiological image deconvolution problem, that of reduction of geometric blurring in magnification mammography.
Birch, Ian   +5 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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