Results 91 to 100 of about 10,268,798 (293)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Finding a Maximum Weight Independent Set of a Circle Graph [PDF]
, 1991 We present an algorithm for finding a maximum weight independent set of a circle graph. For a cicle graph of a set of n chords with N endpoints, the algorithm finds a maximum weight independent set in O(nN) time and O(n) space.Special Section LETTER ...
MUKAIYAMA Akira +2 more
core
Improved Distributed Approximations for Maximum Independent Set [PDF]
, 2020 We present improved results for approximating maximum-weight independent set (MaxIS) in the CONGEST and LOCAL models of distributed computing. Given an input graph, let n and Δ be the number of nodes and maximum degree, respectively, and let MIS(n,Δ) be ...
Kawarabayashi, Ken-ichi +3 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Minimum Connected Dominating Set Algorithms for Ad Hoc Sensor Networks
Sensors, 2019 To achieve effective communication in ad hoc sensor networks, researchers have been working on finding a minimum connected dominating set (MCDS) as a virtual backbone network in practice.
Xuemei Sun, Yongxin Yang, Maode Ma
doaj +1 more source
Maximum independent set and maximum clique algorithms for overlap graphs
Discrete Applied Mathematics, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Eowyn Cenek, Lorna Stewart
openaire +2 more sources
The 0-1 inverse maximum stable set problem [PDF]
Given an instance of a weighted combinatorial optimization problem and its feasible solution, the usual inverse problem is to modify as little as possible (with respect to a fixed norm) the given weight system to make the giiven feasible solution optimal.
Yerim Chung, Marc Demange
core
Maximum weight cycle packing in directed graphs, with application to kidney exchange programs [PDF]
, 2009 Centralized matching programs have been established in several countries to organize kidney exchanges between incompatible patient-donor pairs. At the heart of these programs are algorithms to solve kidney exchange problems, which can be modelled as ...
Biro, P., Rizzi, R., Manlove, D.F.
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source