Results 71 to 80 of about 10,268,798 (293)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A characterization of trees with equal 2-domination and 2-independence numbers [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2017
A set $S$ of vertices in a graph $G$ is a $2$-dominating set if every vertex of $G$ not in $S$ is adjacent to at least two vertices in $S$, and $S$ is a $2$-independent set if every vertex in $S$ is adjacent to at most one vertex of $S$.
Christoph Brause   +2 more
doaj   +1 more source

Approximation hardness of optimization problems in intersection graphs of d-dimensional boxes [PDF]

open access: yes, 2005
The Maximum Independent Set problem in d-box graphs, i.e., in the intersection graphs of axis-parallel rectangles in R d , is a challenge open problem. For any fixed d ≥ 2 the problem is NP-hard and no approximation algorithm with ratio o(log d−1 n) is ...
Chlebikova, Janka   +5 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Power of the Lorentz Quantum Computer

open access: yesEntropy
We analyze the power of the recently proposed Lorentz quantum computer (LQC), a theoretical model leveraging hyperbolic bits (hybits) governed by complex Lorentz transformations.
Qi Zhang, Biao Wu
doaj   +1 more source

Multiobject tracking as maximum weight independent set [PDF]

open access: yesCVPR 2011, 2011
This paper addresses the problem of simultaneous tracking of multiple targets in a video. We first apply object detectors to every video frame. Pairs of detection responses from every two consecutive frames are then used to build a graph of tracklets.
William Brendel   +2 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Finding Near-Optimal Weight Independent Sets at Scale

open access: yesJournal of Graph Algorithms and Applications
Computing maximum weight independent sets in graphs is an important NP-hard optimization problem. The problem is particularly difficult to solve in large graphs for which data reduction techniques do not work well.
Ernestine Großmann   +3 more
doaj   +1 more source

A Novel Defect Tolerance Scheme for Nanocrossbar Architectures with Enhanced Efficiency

open access: yesMicromachines, 2018
The semiconductor industry is now facing challenges to keep pace with Moore’s law and this leads to the requirement of new materials and newer technological devices. Molecular switch-based nanodevices are one of the promising areas because of their
Devisree Sasikumar, Anand Kumar
doaj   +1 more source

Quantum Optimization with Arbitrary Connectivity Using Rydberg Atom Arrays

open access: yesPRX Quantum, 2023
Programmable quantum systems based on Rydberg atom arrays have recently been used for hardware-efficient tests of quantum optimization algorithms [Ebadi et al., Science, 376, 1209 (2022)] with hundreds of qubits.
Minh-Thi Nguyen   +5 more
doaj   +1 more source

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