Results 71 to 80 of about 2,034,768 (362)

Maximum likelihood degree of the two-dimensional linear Gaussian covariance model [PDF]

open access: yesAlg. Stat. 11 (2020) 107-123, 2019
In algebraic statistics, the maximum likelihood degree of a statistical model is the number of complex critical points of its log-likelihood function. A priori knowledge of this number is useful for applying techniques of numerical algebraic geometry to the maximum likelihood estimation problem. We compute the maximum likelihood degree of a generic two-
arxiv   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Modified Maximum Likelihood Estimations of the Epsilon-Skew-Normal Family

open access: yesJournal of Statistical Theory and Applications (JSTA), 2020
In this work, maximum likelihood (ML) estimations of the epsilon-skew-normal (ESN) family are obtained using an EM-algorithm to modify the ordinary estimation already used and solve some of its problems within issues.
Parichehr Jamshidi   +2 more
doaj   +1 more source

Microbial-Maximum Likelihood Estimation Tool for Microbial Quantification in Food From Left-Censored Data Using Maximum Likelihood Estimation for Microbial Risk Assessment

open access: yesFrontiers in Microbiology, 2021
In food microbial measurements, when most or very often bacterial counts are below to the limit of quantification (LOQ) or the limit of detection (LOD) in collected food samples, they are either ignored or a specified value is substituted.
Gyung Jin Bahk, Hyo Jung Lee
doaj   +1 more source

Varieties with maximum likelihood degree one

open access: yes, 2014
We show that algebraic varieties with maximum likelihood degree one are exactly the images of reduced A-discriminantal varieties under monomial maps with finite fibers.
Huh, June
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

New Technique of Near Maximum Likelihood Detection Processes

open access: yesVìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni Kììvsʹkij Polìtehnìčnij Ìnstitut: Serìâ Radìotehnìka, Radìoaparatobuduvannâ, 2016
This paper introduces new detector named newly adaptively designed near maximum likelihood detector (NADD). This detector combines adaptively three types of near maximum likelihood detectors, pseudobinary, pseudoquaternary, and pseudooctonary.
Muhanned AL-Rawi, Muaayed AL-Rawi
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Maximum Likelihood Estimation in the Fractional Vasicek Model

open access: yesLithuanian Journal of Statistics, 2017
We consider the fractional Vasicek model of the form dXt = (α-βXt)dt +γdBHt , driven by fractional Brownian motion BH with Hurst parameter H ∈ (1/2,1).
Stanislav Lohvinenko   +1 more
doaj   +1 more source

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