Results 81 to 90 of about 2,034,768 (362)

The maximum likelihood degree of a chemical reaction at the equilibrium [PDF]

open access: yesarXiv, 2019
The complexity of a maximum likelihood estimation is measured by its maximum likelihood degree ($ML$ degree). In this paper we study the maximum likelihood problem associated to chemical networks composed by one single chemical reaction under the equilibrium assumption.
arxiv  

Maximum Likelihood Duality for Determinantal Varieties

open access: yes, 2012
In a recent paper, Hauenstein, Sturmfels, and the second author discovered a conjectural bijection between critical points of the likelihood function on the complex variety of matrices of rank r and critical points on the complex variety of matrices of ...
Draisma, Jan, Rodriguez, Jose
core   +1 more source

The maximum likelihood prior

open access: yesThe Annals of Statistics, 1998
Consider an estimate $\theta^*$ of a parameter $\theta$ based on repeated observations from a family of densities $f_\theta$ evaluated by the Kullback–Leibler loss function $K(\theta, \theta^*) = \int \log(f_\theta/f_{\theta^*})f_\theta$. The maximum likelihood prior density, if it exists, is the density for which the corresponding Bayes estimate is ...
openaire   +3 more sources

The Epic Story of Maximum Likelihood [PDF]

open access: yesStatistical Science, 2007
Published in at http://dx.doi.org/10.1214/07-STS249 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
openaire   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Maximum likelihood degree of Fermat hypersurfaces via Euler characteristics [PDF]

open access: yesarXiv, 2015
Maximum likelihood degree of a projective variety is the number of critical points of a general likelihood function. In this note, we compute the Maximum likelihood degree of Fermat hypersurfaces. We give a formula of the Maximum likelihood degree in terms of the constants $\beta_{\mu, \nu}$, which is defined to be the number of complex solutions to ...
arxiv  

Observed Range Maximum Likelihood Estimation [PDF]

open access: yes, 2011
The idea of maximizing the likelihood of the observed range for a set of jointly realized counts has been employed in a variety of contexts. The applicability of the MLE introduced in [1] has been extended to the general case of a multivariate sample ...
Markov, Plamen
core  

Maximum-likelihood density modification [PDF]

open access: yesActa Crystallographica Section D Biological Crystallography, 2000
A likelihood-based approach to density modification is developed that can be applied to a wide variety of cases where some information about the electron density at various points in the unit cell is available. The key to the approach consists of developing likelihood functions that represent the probability that a particular value of electron density ...
openaire   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard [PDF]

open access: yesarXiv, 2013
Maximum likelihood is a popular technique for isoform reconstruction. Here, we show that isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard.
arxiv  

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