Results 51 to 60 of about 5,271 (207)

TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition

, 2013
Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors.
Kluger, Yuval, Micsinai, Mariann, Parisi, Fabio, Strino, Francesco   +3 more
core   +1 more source

Ancestral genome estimation reveals the history of ecological diversification in Agrobacterium [PDF]

, 2017
Horizontal gene transfer (HGT) is considered as a major source of innovation in bacteria, and as such is expected to drive adaptation to new ecological niches.
Barbe, V, Bigot, T, Calteau, A, Chapulliot, D, Daubin, V, Dubost, A, Guéguen, L, Lassalle, F, Mornico, D, Muller, D, Nesme, X, Penel, S, Planel, R, Vallenet, D, Vial, L   +14 more
core   +4 more sources

Machine Learning to Predict Remission Between 6 and 24 Months in Rheumatoid Arthritis: Insights From JAK, an International Registry Collaboration

Arthritis &Rheumatology, EarlyView.
Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis, Denis Mongin, Denis Choquette, Louis Coupal, Catalin Codreanu, Florenzo Iannone, Roberto Caporali, Tore K. Kvien, Sella Provan, Ruth Fritsch‐Stork, Dan Nordström, Nina Trokovic, Karel Pavelka, Jakub Závada, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Irini Flouri, Céline Lamacchia, Michele Iudici, Delphine Courvoisier, Kim Lauper, Axel Finckh   +22 more
wiley   +1 more source

Models, algorithms, and programs for phylogeny reconciliation [PDF]

, 2011
International audienceGene sequences contain a gold mine of phylogenetic information. But unfortunately for taxonomists this information does not only tell the story of the species from which it was collected. Genes have their own complex histories which
Berry, Vincent, Daubin, Vincent, Doyon, Jean-Philippe, Ranwez, Vincent   +3 more
core   +3 more sources

A Network Analysis of Alexithymia, Interoception, Empathy, Self‐Awareness and Psychopathological Symptoms in Young People With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with altered interoception, empathy, self‐awareness, and alexithymia. However, limited research has been conducted to investigate the interrelationships of these constructs with psychopathological symptoms.
Antonio Kei‐Fung Shek, Simon S. Y. Lui, Eric C. L. Lai, Raisie W. K. Wong, Jason L. F. Chan, Lok‐Yin Choi, Kimi H. Y. Lam, Eugenia Y. C. Lok, Siu‐Man Lam, Wang Yi, Raymond C. K. Chan   +10 more
wiley   +1 more source

Molecular phylogeny of the genera Palaemon and Palaemonetes (Decapoda, Caridea, Palaemonidae) from a European perspective [PDF]

, 2014
A molecular phylogenetic study by Murphy & Austin (2003) showed that Australian representatives of three shrimp genera of the family Palaemonidae (Palaemon, Palaemonetes, and Macrobrachium) do not cluster according to their generic classification ...
Cuesta, José A., Drake, Pilar, Martínez-Rodríguez, Gonzalo, Rodríguez, Antonio, Schubart, Christoph D.   +4 more
core   +2 more sources

Design of experiments‐driven optimization of Porphyridium marinum cultivation: impact of operational variables on phycoerythrin and exopolysaccharide production

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Among the Porphyridium genus, Porphyridium marinum exhibits the highest phycoerythrin (PE) content. In this study, the metabolic trade‐off between biomass, PE, and sulfated exopolysaccharide (EPS) production was assessed under varying nitrogen and sulfur availability, light intensity, residence time, and cultivation mode.
Rosaria Tizzani, Agnese Torrisi, Fabrizio Bezzo, Eleonora Sforza   +3 more
wiley   +1 more source

ESG Performance, Debt Financing, and R&D Output: Evidence From the Healthcare Sector

Business Strategy and the Environment, EarlyView.
ABSTRACT Amid growing calls for sustainability in the healthcare sector, this study examines how and under what conditions environmental, social, and governance (ESG) performance influences research and development (R&D) output. Although existing studies suggest that ESG performance enhances R&D output, the financial mechanisms that enable or constrain
Sarmad Ali, Oriana Ciani, Simone Ghislandi   +2 more
wiley   +1 more source

Venture Funding: Signals of Environmental Orientation and Their Interplay With Investor‐ and Country‐Level Characteristics

Business Strategy and the Environment, EarlyView.
ABSTRACT Environmentally oriented ventures pursue a dual mission: to create both environmental and financial value. This dual mission adds complexity and can influence ventures' funding prospects, as investors mostly pursue financial motivations.
David Flore, Corinna Vera Hedwig Schmidt, Steffen Strese   +2 more
wiley   +1 more source

Takeover Vulnerability and the Discipline of ESG Overinvestment

Business Strategy and the Environment, EarlyView.
ABSTRACT While takeovers serve a disciplinary role by replacing inefficient managers, the threat of takeovers may compel firms to divert attention from Environmental, Social and Governance (ESG) efforts as a strategic response to external pressure, especially when such firms are already overinvesting in ESG.
Abongeh Tunyi, Ruth O. Sagay, Reon Matemane   +2 more
wiley   +1 more source