Results 31 to 40 of about 391,232 (316)

Principal eigenvalues for k-Hessian operators by maximum principle methods

open access: yesMathematics in Engineering, 2021
For fully nonlinear $k$-Hessian operators on bounded strictly $(k-1)$-convex domains $\Omega$ of $\R^N$, a characterization of the principal eigenvalue associated to a $k$-convex and negative principal eigenfunction will be given as the supremum over ...
Isabeau Birindelli, Kevin R. Payne
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Hopf maximum principle revisited

open access: yesElectronic Journal of Differential Equations, 2015
A weak version of Hopf maximum principle for elliptic equations in divergence form $$ \sum_{i,j=1}^N\partial_i(a_{ij}(x)\partial_ju)=0 $$ with Holder continuous coefficients $a_{ij}$ was shown in [3], in the two-dimensional case.
Jose C. Sabina de Lis
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pontryagin Maximum Principle for Incommensurate Fractional-Orders Optimal Control Problems

open access: yesMathematics, 2023
We introduce a new optimal control problem where the controlled dynamical system depends on multi-order (incommensurate) fractional differential equations.
Faïçal Ndaïrou, Delfim F. M. Torres
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Maximum Entropy Production Principle and Linear Irreversible Processes

open access: yesEntropy, 2010
It is shown that Onsager’s principle of the least dissipation of energy is equivalent to the maximum entropy production principle. It is known that solutions of the linearized Boltzmann equation make extrema of entropy production.
Milan Brumen   +5 more
doaj   +1 more source

Combining experiments and simulations using the maximum entropy principle. [PDF]

open access: yesPLoS Computational Biology, 2014
A key component of computational biology is to compare the results of computer modelling with experimental measurements. Despite substantial progress in the models and algorithms used in many areas of computational biology, such comparisons sometimes ...
Wouter Boomsma   +2 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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