Results 51 to 60 of about 5,003,645 (342)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Thermodynamic resource theories, non-commutativity and maximum entropy principles
New Journal of Physics, 2017 We discuss some features of thermodynamics in the presence of multiple conserved quantities. We prove a generalisation of Landauer principle illustrating tradeoffs between the erasure costs paid in different ‘currencies’.
Matteo Lostaglio +2 more
doaj +1 more source
Strong maximum principles for implicit parabolic functional-differential problems together with nonlocal inequalities with functionals [PDF]
Opuscula Mathematica, 2009 The aim of the paper is to give strong maximum principles for implicit parabolic functional-differential problems together with nonlocal inequalities with functionals in relatively arbitrary \((n+1)\)-dimensional time-space sets more general than the ...
Ludwik Byszewski
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The maximum principle for equations with composite coefficients
Electronic Journal of Differential Equations, 2000 It is well-known that the maximum of the solution of a linear elliptic equation can be estimated in terms of the boundary data provided the coefficient of the gradient term is either integrable to an appropriate power or blows up like a small negative ...
Gary M. Lieberman
doaj
Maximum principles for viscosity solutions of weakly elliptic equations
Bruno Pini Mathematical Analysis Seminar, 2019 Maximum principles play an important role in the theory of elliptic equations. In the last decades there have been many contributions related to the development of fully nonlinear equations and viscosity solutions.
Antonio Vitolo
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Optimal Conditions for Maximum and Antimaximum Principles of the Periodic Solution Problem
Boundary Value Problems, 2010 Given a periodic, integrable potential q(t), we will study conditions on q(t) so that the operator Lqx=x″+qx admits the maximum principle or the antimaximum principle with respect to the periodic boundary condition.
Meirong Zhang
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Journal of the Australian Mathematical Society, 1979 AbstractLet K be a nonempty compact set in a Hausdorff locally convex space, and F a nonempty family of upper semicontinuous convex-like functions from K into [–∞, ∞). K is partially ordered by F in a natural manner. It is shown among other things that each isotone, upper semicontinuous and convex-like function g: K → [ – ∞, ∞) attains its K-maximum at
openaire +2 more sources