Results 41 to 50 of about 358,493 (263)
The maximum principle for equations with composite coefficients
It is well-known that the maximum of the solution of a linear elliptic equation can be estimated in terms of the boundary data provided the coefficient of the gradient term is either integrable to an appropriate power or blows up like a small negative ...
Gary M. Lieberman
doaj
Evolution of non-stationary processes and some maximum entropy principles
This paper studies, by using the speed-gradient principle, the evolution of non-stationary processes in the context of maximization of Varma, weighted Rényi, weighted Varma and Rényi-Tsallis of order α entropies.
Preda Vasile, Băncescu Irina
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Maximum and minimum principles for nonlinear transport equations on discrete-space domains
We consider nonlinear scalar transport equations on the domain with discrete space and continuous time. As a motivation we derive a conservation law on these domains.
Jonas Volek
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Speed-gradient Entropy Principle for Nonstationary Processes
The speed-gradient variational principle (SG-principle) for nonstationary far from equilibrium systems is formulated and illustrated by examples. The SG-model of transient (relaxation) dynamics for systems of a finite number of particles based on maximum
Alexander Fradkov
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Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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Peyronie's Reconstruction for Maximum Length and Girth Gain: Geometrical Principles
Peyronie's disease has been associated with penile shortening and some degree of erectile dysfunction. Surgical reconstruction should be based on giving a functional penis, that is, rectifying the penis with rigidity enough to make the sexual intercourse.
Paulo H. Egydio, Salvatore Sansalone
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The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Uncertainty principles and maximum entropic force
We consider quantum gravity corrections to the maximum entropic force that arise from several gravitational uncertainty principles. These include the Generalized Uncertainty Principle (GUP), the Extended Uncertainty Principle (EUP), the Generalized ...
Jonas Mureika, Elias Vagenas
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