Results 51 to 60 of about 358,493 (263)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Remarks on the strong maximum principle for nonlocal operators
Electronic Journal of Differential Equations, 2008 In this note, we study the existence of a strong maximum principle for the nonlocal operator $$ mathcal{M}[u](x) :=int_{G}J(g)u(x*g^{-1})dmu(g) - u(x), $$ where $G$ is a topological group acting continuously on a Hausdorff space $X$ and $u in C(X)
Jerome Coville
doaj
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Maximum principles, sliding techniques and applications to nonlocal equations
Electronic Journal of Differential Equations, 2007 This paper is devoted to the study of maximum principles holding for some nonlocal diffusion operators defined in (half-) bounded domains and its applications to obtain qualitative behaviors of solutions of some nonlinear problems.
Jerome Coville
doaj
Journal of the Australian Mathematical Society, 1979 AbstractLet K be a nonempty compact set in a Hausdorff locally convex space, and F a nonempty family of upper semicontinuous convex-like functions from K into [–∞, ∞). K is partially ordered by F in a natural manner. It is shown among other things that each isotone, upper semicontinuous and convex-like function g: K → [ – ∞, ∞) attains its K-maximum at
openaire +2 more sources
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Maximum Principles for Dynamic Equations on Time Scales and Their Applications
Journal of Applied Mathematics, 2014 We consider the second dynamic operators of elliptic type on time scales. We establish basic generalized maximum principles and apply them to obtain weak comparison principle for second dynamic elliptic operators and to obtain the uniqueness of Dirichlet
Shuqing Zhou, Hui Li
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source