Results 91 to 100 of about 11,013,929 (238)

Targeted review of the maximum residue levels (MRLs) for dimethomorph

EFSA Journal
Abstract In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a targeted risk assessment for dimethomorph considering the residue definition and the toxicological reference values (TRVs) derived during the renewal of the approval of dimethomorph and the most recent version of the EFSA ...
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A Residue Number System Based Parallel Communication Scheme using Orthogonal Signaling: Part I-System Outline

, 2002
A novel signaling scheme is presented, where a set of orthogonal signals is transmitted in parallel. The signals are selected according to the so-called residue number system (RNS).
Yang, L-L., Hanzo, L.
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Can inorganic fertilizer substitute for organic amendments in the rehabilitation of saline, sodic ore refining residues? [PDF]

, 2003
Organic amendments would generally be attractive additions for revegetation of ore refining residues that mostly contain negligible organic matter. However organic materials may not be available on mine sites in sufficient quantities and are bulky to ...
Fletcher, N., Bell, R.W., Krockenberger, I., Samaraweera, M.K.S.A.   +3 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Revision of the review of the existing maximum residue levels for thiabendazole [PDF]

EFSA Journal, 2016
In compliance with Article 43 of Regulation (EC) No 396/2005, EFSA received from the European Commission a mandate to update its previous review of the existing maximum residue levels (MRLs) for thiabendazole on the basis of the new toxicological reference values as indicated in the EFSA conclusion on the peer review of thiabendazole under Regulation ...
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Modification of the existing maximum residue level for deltamethrin in kale

EFSA Journal, 2018
In accordance with Article 6 of Regulation (EC) No 396/2005, the Agriculture and Horticulture Development Board (AHDB) submitted a request to the competent authority in the United Kingdom (evaluating Member State (EMS)) to modify the existing maximum ...
European Food Safety Authority (EFSA), Alba Brancato, Daniela Brocca, Chloe De Lentdecker, Zoltan Erdos, Lucien Ferreira, Luna Greco, Samira Jarrah, Dimitra Kardassi, Renata Leuschner, Christopher Lythgo, Paula Medina, Ileana Miron, Tunde Molnar, Alexandre Nougadere, Ragnor Pedersen, Hermine Reich, Angela Sacchi, Miguel Santos, Alois Stanek, Juergen Sturma, Tarazona Jose, Theobald Anne, Benedicte Vagenende, Alessia Verani, Laura Villamar‐Bouza   +25 more
doaj   +1 more source