Results 121 to 130 of about 1,263,980 (273)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Wavefunctions and counting formulas for quasiholes of clustered quantum Hall states on a sphere
, 2006 The quasiholes of the Read-Rezayi clustered quantum Hall states are considered, for any number of particles and quasiholes on a sphere, and for any degree k of clustering.
G. E. Andrews +3 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Bayesian models and algorithms for protein beta-sheet prediction [PDF]
, 2009 Prediction of the three-dimensional structure greatly benefits from the information related to secondary structure, solvent accessibility, and non-local contacts that stabilize a protein's structure.
Altunbasak, Yucel +5 more
core
Experimental study of a low-order wavefront sensor for the high-contrast coronagraphic imager EXCEDE
, 2013 The mission EXCEDE (EXoplanetary Circumstellar Environments and Disk Explorer), selected by NASA for technology development, is designed to study the formation, evolution and architectures of exoplanetary systems and characterize circumstellar ...
Belikov, Ruslan +6 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Towards Robustness in Residue Number Systems
, 2016 The problem of robustly reconstructing a large number from its erroneous remainders with respect to several moduli, namely the robust remaindering problem, may occur in many applications including phase unwrapping, frequency detection from several ...
Huo, Haiye, Xia, Xiang-Gen, Xiao, Li
core +1 more source
EFSA journal. European Food Safety Authority, 2019 According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance imidacloprid.
Himdata Abdourahime +29 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Modification of the existing maximum residue level for aminopyralid in maize
EFSA Journal, 2016 In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State (EMS), Hungary, received an application from Dow AgroSciences Ltd to set a maximum residue level (MRL) for the active substance aminopyralid in maize.
European Food Safety Authority (EFSA)
doaj +1 more source