A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Phase stability and mechanical response of the ordered ScTaCo<sub>2</sub>Sb<sub>2</sub> crystal: insights from first-principles calculations. [PDF]
Guo Z +5 more
europepmc +1 more source
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source
Experimental studies on the mechanical properties of garlic scape. [PDF]
Yang J, Xian B, Lin S, Guo X.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Shear-Induced Evolution of Cellular Structure and Thermo-Mechanical Properties in PLA/HNC and In-situ Fibrillated PLA/PTFE Composite Foams. [PDF]
George Raju S +2 more
europepmc +1 more source
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Unveiling the physical properties of AlMgX<sub>3</sub> (X = Cl and I) for emerging energy applications. [PDF]
Zafar H +6 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Pre-Damage Strengthening of Heavy-Duty Steel Crane Girders Using Bonded CFRP Plates for Fatigue Life Enhancement. [PDF]
Zhao X, Liang Y, Jin N, Liu Z.
europepmc +1 more source

