Results 51 to 60 of about 64,706 (306)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Numerical simulation of single- and multi-step shear stress relaxations of isotropic magnetorheological elastomer using fractional derivative viscoelastic models

Archives of Mechanics, 2022
The paper presents numerical simulations of single- and multi-step shear stress relaxations of isotropic magnetorheological elastomer (MRE) using fractional derivative Maxwell and Kelvin–Voigt viscoelastic models. The isotropic MRE has been fabricated by
T.H. Nam, I. Petríková, B. Marvalová
doaj   +1 more source

Dual solutions: Newtonian vs Maxwell model.

, 2015
Dual solutions: Newtonian vs Maxwell model.
Muhammad Awais (263096), Sania Irum (761469), Salman Saleem (827757), Tasawar Hayat (433317)   +3 more
core   +1 more source

A noniterative design procedure for supplemental brace–damper systems in single-degree-of-freedom systems [PDF]

, 2013
In this paper, a method for designing supplemental brace–damper systems in single-degree-of-freedom (SDOF) structures is presented. We include the effects of the supporting brace stiffness in the dynamic response by using a viscoelastic Maxwell model. On
Londoño Monsalve, Julian Mauricio, Neild, Simon A, Neild, S., Londoño, J.M., S. A. Neild, D. J. Wagg, Wagg, David J, Wagg, D.   +7 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Modified generalised maxwell model for hysteretic behavior of elastomeric dampers

, 2020
A constitutive model is presented for the hysteretic behavior of elastomeric material, called the Modified Generalized Maxwell Model (MGMM). A new force-displacement relationship which describes the well known Generalized Maxwell Model (GMM) is also ...
Williams, Martin, Basagiannis, Christos
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

Arthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro, Karen Durrant, William G. Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H. Humphreys   +6 more
wiley   +1 more source

Improved space charge transport model in bi-layer dielectrics—considering carrier dynamic equilibrium

High Voltage, 2020
The Maxwell–Wagner model and bipolar charge transport model both aim at describing the charge transport behaviours in dielectrics. The Maxwell–Wagner model performs well in calculating the polarisation current and electric field distribution, but it is ...
Hucheng Liang, Boxue Du, Jin Li, Hang Yao, Hang Yao, Zehua Wang   +5 more
doaj   +1 more source

Holographic model for light quarks in anisotropic hot dense QGP with external magnetic field

European Physical Journal C: Particles and Fields, 2023
We present a five-dimensional twice anisotropic holographic model supported by Einstein-dilaton-three-Maxwell action describing light quarks. The first of the Maxwell fields provides finite chemical potential.
Irina Ya. Aref’eva, Alexey Ermakov, Kristina Rannu, Pavel Slepov   +3 more
doaj   +1 more source