Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021 [PDF]
Emerging Infectious DiseasesWe detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018–2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D.
Julia Forato +16 more
doaj +5 more sources
Mayaro Virus: An Emerging Alphavirus in the Americas. [PDF]
VirusesMayaro virus (MAYV) is an arbovirus first isolated in Trinidad and Tobago in 1954. MAYV is the causative agent of Mayaro fever, which is characterised by high fever, maculopapular rash, myalgia and arthralgia.
Wei LLL, Tom R, Kim YC.
europepmc +4 more sources
Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease. [PDF]
J Virol, 2023 Mayaro virus (MAYV) is an emerging arbovirus member of the Togaviridae family and Alphavirus genus. MAYV infection causes an acute febrile illness accompanied by persistent polyarthralgia and myalgia.
Santos FM +17 more
europepmc +4 more sources
Mouse Models of Mayaro Virus [PDF]
Viruses, 2023 Mayaro virus (MAYV), the etiologic agent of Mayaro fever, leads patients to severe myalgia and arthralgia, which can have a major impact on public health in all the countries where the virus circulates. The emergence and dissemination of new viruses have
Rafael Borges Rosa +4 more
doaj +3 more sources
Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil [PDF]
BMC Research Notes, 2022 Objective To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017.
Robson dos Santos Souza Marinho +10 more
doaj +3 more sources
Antiviral action of aqueous extracts of propolis from Scaptotrigona aff. postica (Hymenoptera; Apidae) against Zica, Chikungunya, and Mayaro virus. [PDF]
Sci Rep, 2023 The limited availability of antivirals for new highly pathogenic strains of virus has become a serious public health problem that kills thousands of people annually.
Mendonça RZ +3 more
europepmc +3 more sources
A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection. [PDF]
PLoS Neglected Tropical DiseasesThe Mayaro virus (MAYV) is an arthropod-borne virus that causes Mayaro fever, a neglected tropical disease that produces disabling arthralgia. Given the significant threat the dissemination of MAYV poses to global public health, the development of animal
Rafael Borges Rosa +11 more
doaj +4 more sources
Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors [PDF]
Microorganisms, 2021 Despite the emerging threat of the Mayaro virus (MAYV) in Central and South-America, there are no licensed antivirals or vaccines available for this neglected mosquito-borne virus.
Lana Langendries +3 more
doaj +4 more sources
Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein [PDF]
npj VaccinesVirus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus,
Young Chan Kim +13 more
doaj +3 more sources
Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability [PDF]
VirusesThe Mayaro virus (MAYV) is an arbovirus with emerging potential, though with a limited understanding of its epidemiology and evolution due to the lack of studies and surveillance. Here, we investigated 71 MAYV genome sequences from the Americas available
Mikaela dos Santos Marinho +6 more
doaj +3 more sources