Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors [PDF]
Microorganisms, 2021 Despite the emerging threat of the Mayaro virus (MAYV) in Central and South-America, there are no licensed antivirals or vaccines available for this neglected mosquito-borne virus.
Lana Langendries +3 more
doaj +8 more sources
Mayaro virus pathogenesis and immunity in rhesus macaques. [PDF]
PLoS Negl Trop Dis, 2023 Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that causes debilitating and persistent arthritogenic disease. While MAYV was previously reported to infect non-human primates (NHP), characterization of MAYV pathogenesis is currently lacking ...
Weber WC +22 more
europepmc +7 more sources
Mouse Models of Mayaro Virus [PDF]
Viruses, 2023 Mayaro virus (MAYV), the etiologic agent of Mayaro fever, leads patients to severe myalgia and arthralgia, which can have a major impact on public health in all the countries where the virus circulates. The emergence and dissemination of new viruses have
Rafael Borges Rosa +4 more
doaj +5 more sources
Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil [PDF]
BMC Research Notes, 2022 Objective To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017.
Robson dos Santos Souza Marinho +10 more
doaj +5 more sources
Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021 [PDF]
Emerging Infectious DiseasesWe detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018–2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D.
Julia Forato +16 more
doaj +5 more sources
Identification of Mayaro Virus Genotype D in Rondônia, Brazil. [PDF]
Am J Trop Med HygThe Mayaro virus (MAYV) is a significant reemerging arbovirus of public health concern, responsible for outbreaks in several countries including Brazil.
Pimentel EP +7 more
europepmc +6 more sources
A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection. [PDF]
PLoS Neglected Tropical DiseasesThe Mayaro virus (MAYV) is an arthropod-borne virus that causes Mayaro fever, a neglected tropical disease that produces disabling arthralgia. Given the significant threat the dissemination of MAYV poses to global public health, the development of animal
Rafael Borges Rosa +11 more
doaj +3 more sources
Dynamic of Mayaro Virus Transmission in Aedes aegypti, Culex quinquefasciatus Mosquitoes, and a Mice Model. [PDF]
Viruses, 2023 Mayaro virus (MAYV) is transmitted by Haemagogus spp. mosquitoes and has been circulating in Amazon areas in the North and Central West regions of Brazil since the 1980s, with an increase in human case notifications in the last 10 years.
Krokovsky L +5 more
europepmc +4 more sources
Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability [PDF]
VirusesThe Mayaro virus (MAYV) is an arbovirus with emerging potential, though with a limited understanding of its epidemiology and evolution due to the lack of studies and surveillance. Here, we investigated 71 MAYV genome sequences from the Americas available
Mikaela dos Santos Marinho +6 more
doaj +3 more sources
Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein [PDF]
npj VaccinesVirus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus,
Young Chan Kim +13 more
doaj +3 more sources