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Mouse Models of Mayaro Virus [PDF]

Viruses, 2023
Mayaro virus (MAYV), the etiologic agent of Mayaro fever, leads patients to severe myalgia and arthralgia, which can have a major impact on public health in all the countries where the virus circulates. The emergence and dissemination of new viruses have
Rafael Borges Rosa, Emilene Ferreira de Castro, Débora de Oliveira Santos, Murilo Vieira da Silva, Lindomar José Pena   +4 more
doaj   +4 more sources

Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil [PDF]

BMC Research Notes, 2022
Objective To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017.
Robson dos Santos Souza Marinho, Rodrigo Lopes Sanz Duro, Débora Bellini Caldeira, Juliana Galinskas, Mânlio Tasso Oliveira Mota, James Hunter, Maria da Aparecida Rodrigues Teles, Flávio Augusto de Pádua Milagres, Ricardo Sobhie Diaz, Fernando Shinji Kawakubo, Shirley Vasconcelos Komninakis   +10 more
doaj   +4 more sources

Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors [PDF]

Microorganisms, 2021
Despite the emerging threat of the Mayaro virus (MAYV) in Central and South-America, there are no licensed antivirals or vaccines available for this neglected mosquito-borne virus.
Lana Langendries, Rana Abdelnabi, Johan Neyts, Leen Delang   +3 more
doaj   +5 more sources

Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability [PDF]

Viruses
The Mayaro virus (MAYV) is an arbovirus with emerging potential, though with a limited understanding of its epidemiology and evolution due to the lack of studies and surveillance. Here, we investigated 71 MAYV genome sequences from the Americas available
Mikaela dos Santos Marinho, Giulia Magalhães Ferreira, Victória Riquena Grosche, Nilson Nicolau-Junior, Túlio de Lima Campos, Igor Andrade Santos, Ana Carolina Gomes Jardim   +6 more
doaj   +4 more sources

Implementation of in silico methods to predict common epitopes for vaccine development against Chikungunya and Mayaro viruses [PDF]

Heliyon, 2021
Being a Positive sense RNA virus the recent reemergence of Chikungunya and Mayaro virus has taken the concern of the leading scientific communities of the world.
Hammadul Hoque, Rahatul Islam, Srijon Ghosh, Md. Mashiur Rahaman, Nurnabi Azad Jewel, Md. Abunasar Miah   +5 more
doaj   +2 more sources

A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection. [PDF]

PLoS Neglected Tropical Diseases
The Mayaro virus (MAYV) is an arthropod-borne virus that causes Mayaro fever, a neglected tropical disease that produces disabling arthralgia. Given the significant threat the dissemination of MAYV poses to global public health, the development of animal
Rafael Borges Rosa, Emilene Ferreira de Castro, Débora de Oliveira Santos, Willyenne Marília Dantas, Camila Ayumi Tanaka, Renata Pessôa Germano Mendes, Ronaldo Celerino da Silva, Cláudio Antônio de Moura Pereira, João Paulo Silva Servato, Anaíra Ribeiro Guedes Fonseca Costa, Roberta Vieira de Morais Bronzoni, Lindomar José Pena   +11 more
doaj   +2 more sources

Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity [PDF]

Parasites & Vectors, 2014
Background The arthropod-borne Mayaro virus (MAYV) causes ‘Mayaro fever’, a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to
Alda E dos Santos, Ricardo M Kuster, Kristie A Yamamoto, Tiago S Salles, Renata Campos, Marcelo DF de Meneses, Márcia R Soares, Davis Ferreira   +7 more
doaj   +2 more sources

An update on the development of antiviral against Mayaro virus: from molecules to potential viral targets. [PDF]

Arch Microbiol, 2023
Paschoalino M, Marinho MDS, Santos IA, Grosche VR, Martins DOS, Rosa RB, Jardim ACG.   +6 more
europepmc   +3 more sources

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein [PDF]

npj Vaccines
Virus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus,
Young Chan Kim, Yasunori Watanabe, Arlen-Celina Lücke, Xiyong Song, Raquel de Oliveira Souza, Robert Stass, Sasha R. Azar, Shannan L. Rossi, Carla Claser, Beate Mareike Kümmerer, Max Crispin, Thomas A. Bowden, Juha T. Huiskonen, Arturo Reyes-Sandoval   +13 more
doaj   +2 more sources

Bioactive Flavanone Glycoside Isolated from Leaves of <i>Faramea</i> Species Presents Antiviral and Protective Activity against Zika and Mayaro Virus Infection. [PDF]

ACS Omega
Guimarães-Andrade IP, Barboza RS, da Silva MOL, da Conceição RA, de Albuquerque NC, Gavino-Leopoldino D, Neris RLS, de Souza AMT, Valente LMM, Assunção-Miranda I.   +9 more
europepmc   +2 more sources