Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson\u27s Disease. [PDF]
, 2015 BACKGROUND: Preclinical and clinical studies have previously shown that systemic administration of GM1 ganglioside has neuroprotective and neurorestorative properties in Parkinson\u27s disease (PD) models and in PD patients.
Choi, Hyo-S +3 more
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Les psychotropes criminogènes [PDF]
, 2007 Les psychotropes altèrent le psychisme d’un individu et peuvent affecter les perceptions, l’humeur, la conscience, le comportement et diverses fonctions psychologiques et physiques.
Ben Amar, Mohamed
core +1 more source
Updated Clinical Classification of Pulmonary Hypertension [PDF]
, 2013 In 1998, a clinical classification of pulmonary hypertension (PH) was established, categorizing PH into groups which share similar pathological and hemodynamic characteristics and therapeutic approaches.
Simonneau, Gerald +12 more
core +4 more sources
Cocaine influences alcohol-seeking behavior and relapse drinking in alcohol-preferring (P) rats [PDF]
, 2014 BACKGROUND: The results of several studies suggest that there may be common neurocircuits regulating drug-seeking behaviors. Common biological pathways regulating drug-seeking would explain the phenomenon that seeking for 1 drug can be enhanced by ...
Deehan Jr., Gerald A. +4 more
core +1 more source
Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor [PDF]
, 2015 BACKGROUND AND PURPOSE: α7 nicotinic acetylcholine receptors (α7 nAChRs) may represent useful targets for cognitive improvement. The aim of this study is to compare the pro-cognitive activity of selective α7-nAChR ligands, including the partial agonists,
Alexander +41 more
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N-Ethylnorpentylone. Critical Review Report. [PDF]
Substance identification N-Ethylnorpentylone (IUPAC name: 1-(2H-1,3-benzodioxol-5-yl)-2-(ethylamino)pentan-1-one) is a ring-substituted synthetic cathinone analog. It originally emerged in the 1960s during pharmaceutical drug development efforts. Another
Brandt, SD
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Methods in the treatment of obesity [PDF]
, 2000 L'obesitat és una malaltia molt estesa que limita l'activitat i escurça la vida, i que es pot definir com un emmagatzemament patològic de reserves de greix.
Alemany i Lamana, Marià +2 more
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No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy [PDF]
, 2018 We report on four patients with narcolepsy with cataplexy (NC), who were treated with high-dose intravenous immunoglobulins (IVIg). Although in some patients transient effects were seen of both objective (multiple sleep latency test and maintenance of ...
Bassetti, C. +3 more
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Metformin improves the weight reduction effect of mazindol in prediabetic obese Mexican subjects. [PDF]
Int J Clin Pharmacol Ther, 2022 Arguelles-Tello FA +6 more
europepmc +1 more source
Estrategias farmacológicas en el tratamiento de la adicción por cocaína [PDF]
, 2006 Probablemente la cocaína está siendo consumida de forma alarmante debido en parte a la falsa idea de que no iba a producir las devastadoras consecuencias y efectos atribuidos a otras drogas de abuso.
González Moreno, Antonio Manuel
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