Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes [PDF]
Frontiers in Immunology, 2018 The lectin pathway (LP) of complement activation depends on the activation of the MBL-associated serine proteases (MASPs) circulating in complex with mannan-binding lectin (MBL). MBL deficiency is the most common complement deficiency and has been associated with several pathological conditions.
Gérard Van Mierlo +2 more
exaly +5 more sources
High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes
Frontiers in Immunology, 2022 IntroductionAccumulating evidence support that mannan-binding lectin (MBL) is a promising prognostic biomarker for risk-stratification of diabetic micro- and macrovascular complications.
Esben Laugesen +2 more
exaly +3 more sources
Polymorphisms of mbl gene introns and their association with mbl serum levels in hu sheep [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 PCR single-strand conformation polymorphism (SSCP) and DNA sequencing techniques were used to analyze the genetic polymorphism of mannose-binding lectin (MBL) gene 3 introns in Hu sheep.
Mengting ZHAI +6 more
doaj +2 more sources
فراوانی ژنهای متالوبتالاکتاماز و بتالاکتامازهای طیف گسترده در باکتریهای گرم منفی جدا شده از پنومونی وابسته به ونتیلاتور در بخش مراقبتهای ویژه بیمارستان امام رضا(ع) شهر کرمانشاه [PDF]
مجله دانشکده پزشکی اصفهان, 2023 مقاله پژوهشیمقدمه: پنومونی وابسته به ونتیلاتور، شایعترین عفونت اکتسابی بیمارستانی است که مسؤول افزایش مرگ و میر بیماران بستری در بخش مراقبتهای ویژه است.
سپیده کدیوریان +6 more
doaj +1 more source
Phenotypic Tests for Detecting Incidence of Metallo-Β-Lactamase (Mbl) Producing Pseudomonas aeruginosa in Jaipur [PDF]
National Journal of Laboratory Medicine, 2014 Background: Metallo-beta-lactamase (MBL) mediated resistance to carbapenems is an emerging threat in hospital isolates of Pseudomonas aeruginosa.Prompt detection and recognition of MBLs is important for timely implementation of infection control ...
Smita Sood
doaj +1 more source
Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Production of metallo-β-lactamases (MBLs) is an important mechanism of resistance to carbapenems. This study aimed to detect the MBL-producing Pseudomonas aeruginosa clinical isolates and to investigate the presence of blaVIM, blaIMP ...
Mahboubeh Seyedi +3 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2021 Skin and soft tissue infections (SSTIs) are commonly occurring infections with mild to serious clinical manifestations. The incidence of wound sepsis in India ranges from 10-33%1,2. It is important to know the potential microbial pathogens causing wound
V Sheeba +2 more
doaj +1 more source
Drug Resistance Mechanism among Acinetobacter Species
Journal of Pure and Applied Microbiology, 2021 Acinetobacter species cause infections that are difficult to control due to multi-drug resistance and are noted for their intrinsic resistance to antibiotics and for their ability to acquire genes encoding resistance for the production of beta-lactamases
S. Jayashree +2 more
doaj +1 more source
Antibiotic Adjuvant Therapy for Multi-Drug Resistant Carbapenemases Producing Klebsiella pneumoniae Associated Sepsis: A Case Study [PDF]
Journal of Clinical and Diagnostic Research, 2016 Rising resistance and spread of K. pneumoniae strains, create great concerns in treating sepsis patients due to high incidence of mortality and morbidity.
Robin Gupta
doaj +1 more source
Инфекция и иммунитет, 2022 The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova +1 more
doaj +1 more source