Results 31 to 40 of about 41,126 (160)
The number of fatalities caused by multidrug-resistant (MDR) bacteria is over 700,000 annually due to widespread antibiotic usage. So, there is a need of new antibiotics, materials that work like antibiotics, or combinations of antibiotics with ...
Brij Nandan Singh +5 more
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Introduction: Treating Gram-negative bacteria that produce extendedspectrum beta-lactamases (ESBLs), AmpC Beta lactamases, and carbapenemases is a significant clinical concern worldwide. To address this concern, Ceftazidime-Avibactam has been approved
Ravi Kumar Sharma1 +2 more
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MBL: mostly benign lymphocytes, but… [PDF]
In this issue of Blood, Fazi and colleagues have asked important questions and added several new observations to our understanding of monoclonal B-cell lymphocytosis(MBL) in its role as the precursor state of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL).
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Sensitive CSF ELISAs for the detection of MBL, MASP-2 and functional MBL/MASP-2 [PDF]
Mannose binding lectin (MBL) mediated complement pathway is an important constituent of innate immune response in several infections including neuroinflammatory and neurodegenerative diseases. Although there are Enzyme-Linked Immunosorbent Assays (ELISAs) for estimating MBL, MBL-associated serine protease-2 (MASP-2) and functional MBL-MASP-2 (fMBL ...
Janet Y, Kwok +3 more
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The chaperone and potential mannan‐binding lectin (MBL) co‐receptor calreticulin interacts with MBL through the binding site for MBL‐associated serine proteases [PDF]
The chaperone calreticulin has been suggested to function as a C1q and collectin receptor. The interaction of calreticulin with mannan‐binding lectin (MBL) was investigated by solid‐phase binding assays. Calreticulin showed saturable and time‐dependent binding to recombinant MBL, provided that MBL was immobilized on a solid surface or bound to mannan ...
Pagh, Rasmus +9 more
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Crimean Congo hemorrhagic fever among the one-humped camel (Camelus dromedaries) in Central Sudan
Background Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonotic disease caused by Crimean-Congo hemorrhagic fever virus (CCHFV), a member of the genus Nairovirus in the family Bunyaviridae.
Hajer M. Suliman +5 more
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Genetic polymorphisms of mannan binding lectin (MBL), serum levels of MBL, the MBL associated serine protease and H-ficolin in patients with Crohn’s disease [PDF]
The observation of mannan binding lectin (MBL) expression in the small intestine1 suggests that MBL could be a component in the pathogenesis in Crohn’s disease. Seibold et al 2 recently compared the frequencies of MBL polymorphisms in 74 patients with Crohn’s disease with 32 healthy controls, and observed a significantly increased frequency of ...
Nielsen, R G +6 more
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Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19 [PDF]
Abstract Mannan-binding lectin (MBL) and C1q activate the complement cascade via attached serine proteases. The proteases C1r and C1s were initially discovered in a complex with C1q, whereas the MBL-associated serine proteases 1 and 2 (MASP-1 and -2) were discovered in a complex with MBL.
Thiel, S; id_orcid 0000-0002-4817-155X +7 more
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MBL Awards are given for the best paper presented at the General Scientific Meetings by a senior investigator, a junior investigator, a graduate student, and an undergraduate; additional papers are selected for Honorable Mention. The five presentations selected for MBL Awards this year reflect the broad scope of science at the Laboratory.
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Rosy Pandey,1,2 Shyam Kumar Mishra,3,4 Angela Shrestha1 1St. Xavier’s College (Tribhuvan University), Department of Microbiology, Kathmandu, Nepal; 2National Public Health Laboratory, Kathmandu, Nepal; 3UNSW Sydney, School of Optometry and Vision ...
Pandey R, Mishra SK, Shrestha A
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