Marginal Bone Loss Around Bone-Level Fully Guided Implants With Direct Implant Connection Versus Intermediate Abutment: A Randomized Clinical Trial. [PDF]
Gargallo-Albiol J +5 more
europepmc +1 more source
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Cytosolic localization of MBL-1/Muscleblind may be required for ectopic neurite outgrowth in a sensitized background in <i>C. elegans</i>. [PDF]
Lee HMT, Zheng C.
europepmc +1 more source
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
Patient Comfort With Smartphone-Based and Intraoral Camera Imaging in Teledentistry: Observational Cross-Sectional Study. [PDF]
Lucas MB +6 more
europepmc +1 more source
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang +27 more
wiley +1 more source
Safety and feasibility of immediate implant placement in diabetic patients: A systematic review and meta-analysis. [PDF]
Li Z, Yu H, Liang H.
europepmc +1 more source
THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong +16 more
wiley +1 more source
Dental Implants in Patients with Functional Diversity Under a Strict Prevention Protocol: A Retrospective Pilot Study. [PDF]
Silvestre-Rangil J +5 more
europepmc +1 more source
Abstract INTRODUCTION Intrinsic functional connectivity network abnormalities in C9orf72 hexanucleotide repeat expansion carriers emerge during the asymptomatic phase, yet longitudinal studies remain limited. We examined cross‐sectional abnormalities and longitudinal connectivity changes across clinical stages.
Liwen Zhang +23 more
wiley +1 more source

