Peri-Implantitis: Biofilm-Induced Disease or Prosthetically Driven Complication? [PDF]
Roshan Arbaaz B +5 more
europepmc +1 more source
Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology
Abstract INTRODUCTION Lysosomal dysfunction contributes to Alzheimer's disease (AD) by impairing protein clearance and promoting neuroinflammation. Cathepsin H (CTSH), a lysosomal protease, recently emerged as a protective AD locus. We investigated how CTSH is regulated and how it influences early AD pathophysiology.
Cynthia Picard +7 more
wiley +1 more source
Editorial: The oceanic particle flux and its cycling within the deep water column, volume II
Rut Pedrosa-Pamies +3 more
doaj +1 more source
Clinical Efficacy of Narrow-Diameter Tissue-Level Implants for Molar Replacement: A 1-Year Randomised Controlled Trial. [PDF]
Park HW +5 more
europepmc +1 more source
Changes in serum β‐synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Alba Cervantes González +23 more
wiley +1 more source
Macrophage-derived MBL restrains coronavirus-induced pulmonary inflammation by modulating metabolic regulator PKM2-mediated NLRP3 activation. [PDF]
Liu Y +12 more
europepmc +1 more source
Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos +46 more
wiley +1 more source
In vitro activity of aztreonam/avibactam and comparators against Enterobacterales isolates from patients with hospital-acquired pneumonia, ventilator-associated pneumonia, and complicated intra-abdominal infections (ATLAS, 2021-2022). [PDF]
Yang Q +7 more
europepmc +1 more source
Volumetric analysis of root coverage with porcine acellular dermal matrix: Case study
Abstract Background Gingival recession is prevalent and often treated with coronally advanced flap plus connective tissue graft (CAF+CTG). Porcine acellular dermal matrix (PADM) offers a donor‐site‐free alternative. Contemporary digital imaging allows minimally invasive, three‐dimensional (3D) soft‐tissue assessment. This case report quantified 3D soft‐
Edgar Daniel Vargas‐Quiroga +4 more
wiley +1 more source

