Results 51 to 60 of about 989,555 (231)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy

OncoImmunology, 2018
Rationale: Regulatory T cells (Treg) play a pivotal role in the immunosuppressive tumor micro-environment in cancer, including mesothelioma. Recently, the combination of autologous tumor lysate-pulsed dendritic cells (DC) and metronomic cyclophosphamide (
Lisanne Noordam, Margaretha E.H. Kaijen, Koen Bezemer, Robin Cornelissen, Lex A.P.W.M. Maat, Henk C. Hoogsteden, Joachim G.J.V. Aerts, Rudi W. Hendriks, Joost P.J.J Hegmans, Heleen Vroman   +9 more
doaj   +1 more source

Strategies for B-cell receptor repertoire analysis in Primary Immunodeficiencies:From severe combined immunodeficiency to common variable immunodeficiency

Frontiers in Immunology, 2015
The antigen receptor repertoires of B and T cells form the basis of the adaptive immune response. The repertoires should be sufficiently diverse to recognize all possible pathogens.
Hanna eIJspeert, Marjolein eWentink, David evan Zessen, David evan Zessen, Gertjan J Driessen, Virgil A.S.H. Dalm, Martin P van Hagen, Ingrid ePico-Knijnenburg, Erik J Simons, Jacques J.M. van Dongen, Andrew P. Stubbs, Mirjam eVan Der Burg   +11 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Assessing the impact of natural policy experiments on socioeconomic inequalities in health: how to apply commonly used quantitative analytical methods?

BMC Medical Research Methodology, 2017
Background The scientific evidence-base for policies to tackle health inequalities is limited. Natural policy experiments (NPE) have drawn increasing attention as a means to evaluating the effects of policies on health.
Yannan Hu, Frank J. van Lenthe, Rasmus Hoffmann, Karen van Hedel, Johan P. Mackenbach   +4 more
doaj   +1 more source

Broadband MC DS-CDMA Using Space-Time and Frequency-Domain Spreading

, 2002
In this contribution multicarrier direct-sequence code-division multiple-access (MC DS-CDMA) using space-time spreading (STS) assisted transmit diversity and frequency-domain (F-domain) spreading is investigated in the context of broadband communications
Yang, L-L., Hanzo, L.
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Editorial

Manuscript Cultures
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Editorial Team
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Spreading Code Design for a MC-CDMA Based GNSS Pilot Signal [PDF]

, 2010
MC-CDMA can represent an alternative to classical DS-CDMA for the design of GNSS ranging signals. A first requirement MC-CDMA signals must fulfill is that their generation on a satellite payload be feasible.
Meurer, Michael, Seco-Granados, Gonzalo, Vergara, Mariano, Felix Antreich, Gonzalo Seco-Granados, Antreich, Felix, Mariano Vergara, Michael Meurer   +7 more
core   +1 more source