Muscle-derived Mimecan regulates hypothalamus-brown adipose tissue communication and promotes health and lifespan in mice. [PDF]
Mori K, Imai SI.
europepmc +1 more source
Tirzepatide and Metformin Effects on Hunger and BMI in an Adolescent with Hyperphagia and Severe Obesity due to MC4R Deficiency: A Case Report. [PDF]
van der Walle EEPL +3 more
europepmc +1 more source
Inversed impaired osteogenic activity in children with severe obesity due to MC4R deficiency compared to LEP and LEPR deficiency. [PDF]
Janjua QM +8 more
europepmc +1 more source
Genetic architecture of obesity and advances in precision pharmacotherapy: a comprehensive review. [PDF]
Kavaja F, Liehr T, Temaj G.
europepmc +1 more source
Genetic variability in the leptin-melanocortin pathway and its role in weight loss. [PDF]
Santos-Pereira M +4 more
europepmc +1 more source
Efficacy of GLP-1 analog peptides, semaglutide, tirzepatide, and retatrutide on MC4R deficient obesity and their comparison. [PDF]
Hitaka K +3 more
europepmc +1 more source
Genetic variants in the leptin-melanocortin pathway and their joint effects with physical activity and sleep duration on risk of childhood obesity. [PDF]
Liang X +10 more
europepmc +1 more source
The melanocortin receptors as targets for general obesity: contextualizing clinical failures and analyzing future perspectives. [PDF]
Prindle CR +7 more
europepmc +1 more source
Primary cilia and neural computation. [PDF]
Teoh A, Arinjay M, Giri D, Phua SC.
europepmc +1 more source
Causal effect estimation from trans-regulatory single-cell CRISPR screens. [PDF]
Christensen OP +4 more
europepmc +1 more source

