Results 261 to 270 of about 124,045 (313)
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Therapeutic Observations in MCF-7 Aromatase Xenografts
Clinical Cancer Research, 2005Abstract In previous studies using a xenograft model with tumors of human estrogen receptor (ER)–positive breast cancer cells transfected with aromatase (MCF-7Ca), we explored the antitumor efficacy of treatment combining the nonsteroidal aromatase inhibitor letrozole with tamoxifen.
Angela, Brodie +5 more
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Effect of 5‐aminolevulinic acid‐mediated photodynamic therapy on MCF‐7 and MCF‐7/ADR cells
Lasers in Surgery and Medicine, 2004AbstractBackground and ObjectivesPhotodynamic therapy (PDT) has been proposed as an alternative approach in overcoming multidrug resistance (MDR) phenotype. To verify whether 5‐aminolevulinic acid (ALA)‐mediated PDT is effective in MDR cells, we studied the protoporphyrin IX (PpIX) content, intracellular localization, and phototoxicity in human breast ...
Tsuimin, Tsai +5 more
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Invasive and metastatic properties of MCF‐7 cells and rasH‐transfected MCF‐7 cell lines
International Journal of Cancer, 1992AbstractIn vitro invasion and in vivo metastasis assays were performed with a panel of MCF‐7 cells transfected with isogenic constructs of mutated rasH genes. Both increased levels of rasH expression and rasH oncogene activation increased activity of derivative cell lines in in vitro invasion assays.
Gelmann, Edward P. +2 more
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Radiation‐induced gene expression in MCF‐7 cells
International Journal of Radiation Biology, 2003Detection of gene targets applicable to biological dosimetry and early detection of radiation-induced cell damage.MCF-7 human mammary carcinoma cells were exposed to 2 and 6 Gy X-rays. Expression of 1176 genes was traced with the Atlas Human 1.2 Array (Clontech).(1) Based on data reproducibility (about 98%), a new and improved analysis was employed. (2)
T, Stassen, M, Port, I, Nuyken, M, Abend
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Catecholestrogens are MCF-7 cell estrogen receptor agonists
The Journal of Steroid Biochemistry and Molecular Biology, 1993Catecholestrogens are important metabolites of estradiol and estrone in the human. Considerable interest has focused on the catecholestrogens 2-hydroxy- and 4-hydroxyestradiol since they bind to the estrogen receptor with an affinity in the range of estradiol.
N, Schütze +4 more
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Prolidase in human breast cancer MCF-7 cells
Cancer Letters, 1998Prolidase (EC 3.4.13.9) is an ubiquitously distributed imidodipeptidase that catalyzes the hydrolysis of dipeptides containing C-terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline for collagen synthesis and cell growth.
J A, Palka, J M, Phang
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