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Low pO2 and β-Estradiol Induce VEGF in MCF-7 and MCF-7-5C Cells: Relationship to in vivo Hypoxia
Breast Cancer Research and Treatment, 2001Previous work from this laboratory demonstrated that MCF-7 breast carcinoma cells grown in nude mice contained minimal hypoxia but that tamoxifen treatment of these tumors resulted in increased hypoxia (Evans S. et al., Cancer Research, 1997). These findings led to studies exploring the link between estrogen signaling and tumor oxygenation and ...
A, Maity +4 more
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Anticancer activity of VmCT1 analogs against MCF‐7 cells
Chemical Biology & Drug Design, 2017Antimicrobial peptides are considered promising drug candidates due to their broad range of activity. VmCT1 (Phe–Leu–Gly–Ala–Leu–Trp–Asn–Val–Ala–Lys–Ser–Val–Phe–NH2) is an α‐helical antimicrobial peptide that was obtained from the Vaejovis mexicanus smithi scorpion venom. Some of its analogs showed to be as antimicrobial as the wild type, and they were
Cibele Nicolaski Pedron +6 more
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Insulin can modulate MCF-7 cell response to paclitaxel
Cancer Letters, 2004Insulin regulates metabolism through homologous receptor tyrosine kinases, and plays a role in proliferation of breast cancer cells. Our research studied whether insulin, administered separately or in combination with paclitaxel, interferes with paclitaxel-mediated biological activity in human breast cancer cells.
MIGLIETTA, Antonella +4 more
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2012
We show the higher resistance of cancer cells MCF-7 spheroid culture (3D-model) to the absence of serum factors in culture medium in comparison with standard cultivation conditions and with monolayer growth (2D-model) that is evidenced by the index of living cells, apoptic index, distribution of the cells by cycle phases, and adhesive properties.
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We show the higher resistance of cancer cells MCF-7 spheroid culture (3D-model) to the absence of serum factors in culture medium in comparison with standard cultivation conditions and with monolayer growth (2D-model) that is evidenced by the index of living cells, apoptic index, distribution of the cells by cycle phases, and adhesive properties.
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2010
The influence of fullerenes C60 on adhesive characteristics of breast adenocarcinoma cells MCF-7 is studied. It is shown that fullerenes C60 in concentration 10^???5 ?? decrease the cells adhesion to substrate in 2, 5, and 7 days of the incubation of cells in unfed culture in comparison with control.
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The influence of fullerenes C60 on adhesive characteristics of breast adenocarcinoma cells MCF-7 is studied. It is shown that fullerenes C60 in concentration 10^???5 ?? decrease the cells adhesion to substrate in 2, 5, and 7 days of the incubation of cells in unfed culture in comparison with control.
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2015
The analysis of the sensitivity of MCF-7 cells with adaptor protein Rukl/CIN85 overexpression to certain antitumor drugs is performed, and the activity of components of regulatory systems potentially involved in the development of chemoresistance is investigated.
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The analysis of the sensitivity of MCF-7 cells with adaptor protein Rukl/CIN85 overexpression to certain antitumor drugs is performed, and the activity of components of regulatory systems potentially involved in the development of chemoresistance is investigated.
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Tamoxifen induces hypoxia in MCF-7 xenografts.
Cancer research, 1997Tamoxifen is widely used as an adjunct therapy for breast cancer. We hypothesized that hypoxia develops in tumors as a result of tamoxifen treatment because tamoxifen has been reported to be antiangiogenic and thrombogenic. MCF-7 breast tumors were grown under estrogenic stimulation in 4-6-week-old CD-1 nu/nu female mice.
S M, Evans +5 more
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17 Studies on glycoprotein expression differences between MCF-7 and MCF-7-Z
European Journal of Cancer, 2014J. Ner-Kluza +4 more
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โรคมะเร็งเต้านมจัดว่าเป็นโรคมะเร็งที่พบมากเป็นอันดับหนึ่งในเพศหญิง เป้าหมายหลักของการใช้รังสีในการรักษาโรคมะเร็งเต้านม คือการให้รังสีพลังงานสูงแก่เซลล์มะเร็ง โดยที่เซลล์ปกติข้างเคียงได้รับผลกระทบจากรังสีน้อยที่สุด อย่างไรก็ตาม ประสิทธิภาพของการใช้รังสีรักษาสามารถที่จะพัฒนาให้สูงมากยิ่งขึ้นได้ โดยการใช้รังสีรักษาร่วมกับวิธีการรักษาแบบอื่น เช่น การใช้ร ...
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2012
????????i?????????? ?????????? ??i????????i??, i????????i???? ???? i????????i??????????i?????????? ?????????????? ??????????-1 (IGF-1) ???? ??????????????i?? Ruk/CIN85. ????????????????, ???? ??????????????i?? Ruk/CIN85 ?? ????i?????????? ???????????????????????????? ?????????????? ???????????? ???????????? MCF-7 ???? ????i?????????????? ???? ???????? ?
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????????i?????????? ?????????? ??i????????i??, i????????i???? ???? i????????i??????????i?????????? ?????????????? ??????????-1 (IGF-1) ???? ??????????????i?? Ruk/CIN85. ????????????????, ???? ??????????????i?? Ruk/CIN85 ?? ????i?????????? ???????????????????????????? ?????????????? ???????????? ???????????? MCF-7 ???? ????i?????????????? ???? ???????? ?
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