Results 261 to 270 of about 7,687,713 (299)

MCF-7 cells lack the expression of Caspase-3

International Journal of Biological Macromolecules, 2023
With great interest, we read the paper "Chitosan nano-vehicles as biocompatible delivering tools for a new Ag(I)curcuminoid-Gboxin analog complex in cancer and inflammation therapy" published in the International Journal of Biological Macromolecules.
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Radiation‐induced gene expression in MCF‐7 cells

International Journal of Radiation Biology, 2003
Detection of gene targets applicable to biological dosimetry and early detection of radiation-induced cell damage.MCF-7 human mammary carcinoma cells were exposed to 2 and 6 Gy X-rays. Expression of 1176 genes was traced with the Atlas Human 1.2 Array (Clontech).(1) Based on data reproducibility (about 98%), a new and improved analysis was employed. (2)
T, Stassen, M, Port, I, Nuyken, M, Abend
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Actions of insulin on MCF-7 cells that are synchronized with hydroxyurea

Molecular and Cellular Endocrinology, 1987
The role of insulin in stimulating metabolic processes in MCF-7 cells was studied in cells synchronized at the G1:S interphase of the cell cycle using hydroxyurea. Cells released from the hydroxyurea block progressed through one S-phase of the cell cycle when insulin was absent from the medium.
B E, Linebaugh, J A, Rillema
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Downregulation of SOK1 promotes the migration of MCF-7 cells

Biochemical and Biophysical Research Communications, 2011
SOK1 is a member of the germinal center kinase (GCK-III) subfamily but little is known about it, particularly with respect to its role in signal transduction pathways relative to tumor metastasis. By stably transfecting SOK1 siRNA into the MCF-7 breast cancer cell line we found that SOK1 promotes the migration of MCF-7 cells, as determined using wound ...
Xu-Dong, Chen, Chien-Yu, Cho
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Catecholestrogens are MCF-7 cell estrogen receptor agonists

The Journal of Steroid Biochemistry and Molecular Biology, 1993
Catecholestrogens are important metabolites of estradiol and estrone in the human. Considerable interest has focused on the catecholestrogens 2-hydroxy- and 4-hydroxyestradiol since they bind to the estrogen receptor with an affinity in the range of estradiol.
N, Schütze, G, Vollmer, I, Tiemann, M, Geiger, R, Knuppen   +4 more
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Antiestrogenic Effects of LY 117018 in MCF-7 Cells

Endocrinology, 1983
LY 117018 is a nonsteroidal compound which has been shown to antagonize more effectively than tamoxifen the effects of estradiol in rats and mice. We have further defined the properties of this compound on cell growth and progesterone receptor (PR) induction and have compared inhibitory effects to relative binding affinity in a human breast cancer cell
S M, Scholl, K K, Huff, M E, Lippman
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Prolidase in human breast cancer MCF-7 cells

Cancer Letters, 1998
Prolidase (EC 3.4.13.9) is an ubiquitously distributed imidodipeptidase that catalyzes the hydrolysis of dipeptides containing C-terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline for collagen synthesis and cell growth.
J A, Palka, J M, Phang
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Disruption of Mitochondrial Respiration by Melatonin in MCF-7 Cells

Toxicology and Applied Pharmacology, 2001
Clinical and laboratory studies have provided evidence of oncostatic activity by the pineal neurohormone melatonin. However, these studies have not elucidated its mechanism of action. The following series of MCF-7 breast tumor cell studies conducted in the absence of exogenous steroid hormones provide evidence for a novel mechanism of oncostatic ...
A E, Scott, G N, Cosma, A A, Frank, R L, Wells, H S, Gardner   +4 more
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?????????????????????? 3D-???????????????? ???????????? MCF-7 ?? ???????????????????????????????? ????????????????????

2012
We show the higher resistance of cancer cells MCF-7 spheroid culture (3D-model) to the absence of serum factors in culture medium in comparison with standard cultivation conditions and with monolayer growth (2D-model) that is evidenced by the index of living cells, apoptic index, distribution of the cells by cycle phases, and adhesive properties.
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?????????? ?????????????????? C60 ???? ?????????????????? ?????????????????????? ???????????? ???????? ???????????????? ???????????? MCF-7

2010
The influence of fullerenes C60 on adhesive characteristics of breast adenocarcinoma cells MCF-7 is studied. It is shown that fullerenes C60 in concentration 10^???5 ?? decrease the cells adhesion to substrate in 2, 5, and 7 days of the incubation of cells in unfed culture in comparison with control.
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