Results 271 to 280 of about 124,045 (313)

Phosphatidylcholine catabolism in the MCF-7 cell cycle

Biochemistry and Cell Biology, 2006
The catabolism of phosphatidylcholine (PtdCho) appears to play a key role in regulating the net accumulation of the lipid in the cell cycle. Current protocols for measuring the degradation of PtdCho at specific cell-cycle phases require prolonged periods of incubation with radiolabelled choline.
Weiyang, Lin, Gilbert, Arthur
openaire   +2 more sources

Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2.

The Journal of steroid biochemistry and molecular biology, 1998
Androgen and estrogen metabolism was investigated in the hormone-dependent human breast cancer cell line MCF-7 and its two hormone-resistant sublines MCF-7/LCC1 and MCF-7/LCC2. Using the product isolation method, the activity of aromatase, 5alpha-reductase, 3alpha/beta-hydroxysteroid oxidoreductase and 17beta-hydroxysteroid oxidoreductase were ...
Jørgensen, L, Brünner, N, Spang-Thomsen, M, James, M R, Clarke, R, Dombernowsky, P, Svenstrup, B   +6 more
openaire   +2 more sources

Effects of catechin, diclofenac and celecoxib on the proliferation of MCF-7 and LTED MCF-7 cells

Biomedicine & Preventive Nutrition, 2011
Abstract Breast cancer is common among women especially after menopause. Inflammation is now considered as a risk factor of cancer and cyclooxygenase-2 (COX-2) enzymes are highly expressed in many cancers. COX-2 is the inducible enzyme responsible for the synthesis of pro-inflammatory prostaglandins. There are evidences that COX inhibitors especially
N. Sookvanichsilp, K. Poemsantitham
openaire   +1 more source

Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells

Cancer Letters, 2005
Human mammary carcinoma MCF-7 cell line responsiveness to the pteridines xanthopterin and isoxanthopterin was studied using the MTS assay for measurement of cell viability. The pteridines were tested at concentrations ranging from 7.8 to 500 microM singly and in 11 isoxanthopterin:xanthopterin ratios. IC50s of xanthopterin and isoxanthopterin were 109+/
Jean L, Lord, Ann, de Peyster, P J E, Quintana, Robert P, Metzger   +3 more
openaire   +2 more sources

MCF-7 cells lack the expression of Caspase-3

International Journal of Biological Macromolecules, 2023
With great interest, we read the paper "Chitosan nano-vehicles as biocompatible delivering tools for a new Ag(I)curcuminoid-Gboxin analog complex in cancer and inflammation therapy" published in the International Journal of Biological Macromolecules.
openaire   +2 more sources

Optimization of estrogen growth response in MCF-7 cells

In Vitro Cellular & Developmental Biology - Animal, 1992
The factors involved in estradiol-17 beta induced growth stimulation of MCF-7 human breast cancer cells have been examined. Wild type MCF-7 cells (and clone E3) were shown to undergo slow growth in phenol-red-free medium containing specific calf sera. The E3 clone was used to document a mean 6-day growth stimulation of 3.35-fold (doubling time = 33 +/-
T E, Wiese, L G, Kral, K E, Dennis, W B, Butler, S C, Brooks   +4 more
openaire   +2 more sources

Low pO2 and β-Estradiol Induce VEGF in MCF-7 and MCF-7-5C Cells: Relationship to in vivo Hypoxia

Breast Cancer Research and Treatment, 2001
Previous work from this laboratory demonstrated that MCF-7 breast carcinoma cells grown in nude mice contained minimal hypoxia but that tamoxifen treatment of these tumors resulted in increased hypoxia (Evans S. et al., Cancer Research, 1997). These findings led to studies exploring the link between estrogen signaling and tumor oxygenation and ...
A, Maity, W, Sall, C J, Koch, P R, Oprysko, S M, Evans   +4 more
openaire   +2 more sources

Anticancer activity of VmCT1 analogs against MCF‐7 cells

Chemical Biology & Drug Design, 2017
Antimicrobial peptides are considered promising drug candidates due to their broad range of activity. VmCT1 (Phe–Leu–Gly–Ala–Leu–Trp–Asn–Val–Ala–Lys–Ser–Val–Phe–NH2) is an α‐helical antimicrobial peptide that was obtained from the Vaejovis mexicanus smithi scorpion venom. Some of its analogs showed to be as antimicrobial as the wild type, and they were
Cibele Nicolaski Pedron, Gislaine Patricia Andrade, Roseli Hiromi Sato, Marcelo Der Torossian Torres, Giselle Cerchiaro, Anderson Orzari Ribeiro, Vani Xavier Oliveira   +6 more
openaire   +2 more sources

Insulin can modulate MCF-7 cell response to paclitaxel

Cancer Letters, 2004
Insulin regulates metabolism through homologous receptor tyrosine kinases, and plays a role in proliferation of breast cancer cells. Our research studied whether insulin, administered separately or in combination with paclitaxel, interferes with paclitaxel-mediated biological activity in human breast cancer cells.
MIGLIETTA, Antonella, PANNO ML, BOZZO, FRANCESCA, GABRIEL, Ludovica, BOCCA, Claudia   +4 more
openaire   +2 more sources

?????????????????????? 3D-???????????????? ???????????? MCF-7 ?? ???????????????????????????????? ????????????????????

2012
We show the higher resistance of cancer cells MCF-7 spheroid culture (3D-model) to the absence of serum factors in culture medium in comparison with standard cultivation conditions and with monolayer growth (2D-model) that is evidenced by the index of living cells, apoptic index, distribution of the cells by cycle phases, and adhesive properties.
openaire   +1 more source