Results 91 to 100 of about 78,177 (302)

Synthesis and Photophysical Properties of Star‐Shaped Triphenylamine Trimers Functionalized With BODIPY and Subphthalocyanine Chromophores

open access: yesChemistry – A European Journal, EarlyView.
This study investigates how molecular topology influences the photophysical properties of star‐shaped, threefold‐symmetric triphenylamine (TPA) derivatives functionalized with three BODIPY or SubPc units. Their absorption spectra exhibit minimal solvatochromism, whereas their fluorescence intensity is strongly dependent on solvent polarity.
Habiba Boughanmi   +4 more
wiley   +1 more source

Participation of melanin-concentrating hormone (MCH)-positive and MCH - negative nesfatin-1/NUCB2 (nesfatin) neurons in the sleep - wake cycle.

open access: yes, 2013
A–C. Illustrative pictures of the lateral hypothalamic area demonstrating the results of the triple fluorescent immunostainings for nesfatin (red), MCH (blue) and Fos (green) in a home cage kept (A), a rapid eye movement sleep (REMS) - deprived (B) and a
Dorottya Pap (396996)   +8 more
core   +1 more source

Thermodynamic Insights on Isodesmic Perylene Bisimide Dye Aggregation From Concentration‐, Solvent‐ and Temperature‐Dependent Studies

open access: yesChemistry – A European Journal, EarlyView.
The reliability of solvent‐ and temperature‐dependent UV–vis absorption studies was assessed for the isodesmic self‐assembly of a perylene bisimide (PBI), considering the solvatochromic and thermochromic effects for this chromophore. The obtained thermodynamic parameters are compared to reference values from the concentration‐dependent analysis ...
Franziska Schneider   +2 more
wiley   +1 more source

Comprehensive analysis of cutaneous adverse drug reactions during hospitalization: unveiling nuanced complexities and ensuring patient safety

open access: yesJournal of Applied Pharmaceutical Research
Background: The spectrum of cutaneous drug reactions encompasses a broad range from benign rashes to potentially life-threatening conditions. The present study aims to comprehensively investigate the frequency, type, causality, preventability, and ...
Junaid Ahmad Ahangar   +3 more
doaj   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

open access: yesCytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson   +8 more
wiley   +1 more source

A. Binding of IgG to orexin and MCH neurons and CSF MCH levels in narcolepsy patients.

open access: yes, 2015
Co-localisation of serum IgG binding (green), orexin immunoreactivity (red) and MCH immunorecativity (purple) showed co-localization of IgG binding with both orexin and MCH neurons. B.
Dominic Cottrell (758016)   +9 more
core   +1 more source

Fixation Induces Mislocalization of Thin Filament Components in Caenorhabditis elegans Striated Muscle

open access: yesCytoskeleton, EarlyView.
ABSTRACT The simple nematode Caenorhabditis elegans has long served as a powerful genetic model system for studying muscle structure and function, with sarcomeres of the striated body wall muscle (BWM) that are considered largely homologous to those in vertebrates.
Michael J. Kimmich   +3 more
wiley   +1 more source

How to Optimize Healthy Volunteer Screening and Enrolment in Clinical Trials: A Qualitative and Quantitative Approach to Evaluate Processes and Healthy Volunteers' Perceptions

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer   +10 more
wiley   +1 more source

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