Results 141 to 150 of about 78,177 (302)

Dopamine‐Deficiency‐Related Reorganization of the Somatomotor Network in Prodromal and Early Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Introduction Network attack tolerance (NAT) measures the brain's ability to sustain information flow despite the loss of critical brain regions. In Parkinson's disease (PD), NAT has been linked to cognitive and motor function. However, it remains unclear how dopaminergic degeneration shapes NAT, and whether it relates to motor symptom ...
Adrian L. Asendorf   +3 more
wiley   +1 more source

Toward Inter‐Sonication Monitoring of Skull and Brain Temperatures in Transcranial MRgFUS Using a 3D Stack‐of‐Spirals Sequence

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an MRI approach for simultaneous skull and brain temperature monitoring between sonications in transcranial MR‐guided focused ultrasound (MRgFUS) surgeries. Methods A 3D stack‐of‐spirals dual‐echo ultra‐short TE (UTE) sequence incorporating fat suppression, spiral deblurring, trajectory measurement, and B1 correction was ...
Sheng Chen   +4 more
wiley   +1 more source

Integrated enhanced recovery after surgery protocol in radical cystectomy for bladder tumour—A retroprospective study

open access: yesBJUI Compass
Introduction Enhanced recovery after surgery (ERAS) is a patient‐centerd, evidence‐based approach to improve postoperative outcomes. The protocol involves multidisciplinary collaboration and standardisation of perioperative interventions.
Waseem Ashraf   +6 more
doaj   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij   +11 more
wiley   +1 more source

Methodological quality of systematic reviews on treatments in stroke rehabilitation: A cross‐sectional study

open access: yesPM&R, EarlyView.
Abstract Objective Although high‐quality systematic reviews (SRs) could provide reliable evidence on the effectiveness of stroke rehabilitation treatments, methodological flaws may weaken their trustworthiness. This study aimed to evaluate the methodological quality of an up‐to‐date sample of SRs on stroke rehabilitation treatments. Literature survey A
Yin Ting Chan   +7 more
wiley   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Gold‐Modified Mesoporous Carbon Enables Serum Metabolic Fingerprinting for Papillary Thyroid Carcinoma Diagnosis

open access: yesSmall Methods, EarlyView.
A novel MCHS‑Au‑LA substrate is developed for carbon‑gold nanostructure‐initiator mass spectrometry (C‑Au‑NIMS), which acquires metabolic fingerprints of serum samples from papillary thyroid carcinoma (PTC), benign thyroid nodules (BTN), and healthy controls (HC).
Wanwan Yi   +8 more
wiley   +1 more source

Low‐Frequency Noise and Stability in Electrolyte‐Gated Nanoscale Silicon Field‐Effect Transistor Sensors

open access: yesSmall Methods, EarlyView.
Electrolyte‐gated nanoscale silicon field‐effect transistor sensors provide exceptional charge sensitivity and direct electrical readout. However, their sensing accuracy is fundamentally limited by low‐frequency noise and baseline drift. This review examines the origins of noise and drift in these sensors, summarizes the key mitigation strategies, and ...
Yingtao Yu   +5 more
wiley   +1 more source

Financial Development, Income Inequality, and Trade

open access: yesSouthern Economic Journal, EarlyView.
ABSTRACT This study examines the impact of financial development (FD) on income inequality in a general‐equilibrium model with credit constraints and international trade. I show that a single mechanism—the interaction between financial and trade selection effects—reconciles a range of seemingly conflicting results: FD always reduces inequality between ...
Yiming Zhou
wiley   +1 more source

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